Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (41): 7787-7790.doi: 10.3969/j.issn.1673-8225.2011.41.047

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Heat shock protein 70 mRNA expression in peripheral white blood cells after Taiji-quan exercise

Yang De-hong1, Wei Yong2   

  1. 1Department of Physicial Education, Shanghai Institute of Technology, Shanghai  201418, China
    2School of Sports Science, Shanghai University of Sport, Shanghai 200438, China
  • Received:2011-07-07 Revised:2011-08-18 Online:2011-10-08 Published:2011-10-08
  • About author:Yang De-hong★, Master, Lecturer, Department of Physicial Education, Shanghai Institute of Technology, Shanghai 201418, China dehongy@126.com
  • Supported by:

    a grant from Yong Teachers Foundation of Shanghai Committee of Education, No.03LQ05*; Shanghai Key Subjects Construction Program, No.S30802*

Abstract:

BACKGROUND: Several studies have demonstrated that Taiji-quan exercise is promosing to improve organism’s immune function and then postpone aging, but the underlying mechanisms remain poorly understood.
OBJECTIVE: To investigate the heat shock protein 70 (HSP70) expression in peripheral white blood cells after Taiji-quan exercise.
METHODS: The HSP70 mRNA expression was detected by real-time quantitative PCR in peripheral white blood cells of healthy middle-aged and elderly women before, 3 and 6 months after Taiji-Quan exercise.
RESULTS AND CONCLUSION: After 3 months of intensive Taiji-Quan exercise, HSP70 mRNA expression was slightly, but not significantly, increased, compared with before Taiji-Quan exercise. After 6 months of Taiji-Quan exercise, HSP70 mRNA expression was significantly decreased, compared with before exercise and after 3 months of Taiji-Quan exercise. These results suggest that HSP70 mRNA expression can reflect the health benefits of 48-style Taiji-Quan exercise in middle-aged and elderly women and HSP 70 may be the potentioal molecular biological mechanism.

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