Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (38): 7189-7192.doi: 10.3969/j.issn.1673-8225.2011.38.038

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Characteristics of nano-artificial bone graft in treatment of tibial plateau fracture

Cao Yang1, Yuan Zi-ming2, Yan Peng1, Bi Yun-long1   

  1. 1Department of Orthopaedics, First Affiliated Hospital, Liaoning Medical University, Jinzhou  121000, Liaoning Province, China
    2Department of Orthopaedics, Heishan First People’s Hospital, Heishan  121400, Liaoning Province, China
  • Received:2011-04-08 Revised:2011-07-09 Online:2011-09-17 Published:2011-09-17
  • About author:Cao Yang☆, Doctor, Associate professor, Department of Orthopaedics, First Affiliated Hospital, Liaoning Medical University, Jinzhou 121000, Liaoning Province, China cyclcmh@sina.com
  • Supported by:

    the Medical Peak Construction Program of Health Department of Liaoning Province, No. 2010071*

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Abstract:

BACKGROUND: After resetting, tibial plateau fracture always induces great defects of cancellous bone, which requires effective bone graft packing and internal fixation treatment.
OBJECTIVE: To explore the application characteristics of nano-artificial bone graft in treatment of tibial plateau fracture.
METHODS: We retrieved Wanfang Database (http://www.wanfangdata.com.cn/) for articles concerning nano-artificial bone graft in treatment of tibial plateau fracture published from January 1990 to December 2010. The key words were “nano-artificial bone, tibia, fracture”. A total of 48 articles were searched, and 20 were included. Simultaneously, 42 tibial plateau fracture cases undergoing nano-artificial bone graft combined with internal fixation with locking plate system were retrospectively analyzed.
RESULTS AND CONCLUSION: A total of 42 patients were followed up for 6 months to 2 years and 6 months, averagely 15 months. The duration of fracture healing was 3-8 months, averagely 4.2 months. According to Merchant criteria, there were excellent in 39 cases, good in 2 cases, and average in 1 case. Retrieval analysis suggests that nano-artificial bone is a biomaterial prepared by nanometer technique, and is an ideal bone repair material. Artificial bone graft for treatment of tibial plateau fracture can effectively avoid fracture redisplacement and the loss of articular surface height, as well as have characteristics of good biocompatibility, good bone conductibility, small trauma and firm fixation, no rejection or allergic response. Thus, it has extensive application prospect.

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