Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (36): 6821-6824.doi: 10.3969/j.issn.1673-8225.2011.36.040

Previous Articles     Next Articles

Basic and clinical research of autologous bone marrow stem cells in treatment of hepatic cirrhosis

Xing Ni-ni, Li Xiao-sheng   

  1. Department of Gastroenterology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing  400010, China
  • Received:2011-02-28 Revised:2011-04-27 Online:2011-09-03 Published:2011-09-03
  • Contact: Li Xiao-sheng, Master, Professor, Master’s supervisor, Department of Gastroenterology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China LXS6896@126.com
  • About author:Xing Ni-ni★, Studying for master's degree, Department of Gastroenterology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China nx0912@163.com
  • Supported by:

    the Natural Science Foundation of Chongqing Science and Technology Committee, No.2006B135428*

PDF

337

Abstract:

BACKGROUND: Liver transplantation is still facing many problems, such as lack of donor livers, immune rejection after transplantation and its high costs, thus making it restricted in clinic application.
OBJECTIVE: To describe autologous bone marrow stem cell transplantation in the clinical stage as one of the most promising technology that autologous bone marrow stem cells can differentiate into mature liver cells to replace the damaged liver functioning, which can improve symptoms and quality of life in patients.
METHODS: A computer-based online search of PubMed database, CNKI, Wanfang database and VIP database was performed for articles regarding autologous bone marrow stem cells to treat hepatic cirrhosis, with the key words of “bone marrow stem cell, autologous bone marrow stem cell transplantation, hepatic cirrhosis” in Chinese and “bone marrow stem cell, autologous bone marrow stem cell, hepatic cirrhosis” in English. Relevant articles published in recent years or in authorized journals were preferred. Repetitive studies were excluded. Finally, 20 articles were included.
RESULTS AND CONCLUSION: Basic and clinical research about autologous bone marrow stem cell transplantation indicate that autologous bone marrow stem cell transplantation has a broad prospect in the treatment of hepatic cirrhosis.

CLC Number: