Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (23): 4336-4339.doi: 10.3969/j.issn.1673-8225.2011.23.036

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Stem cells for cerebral palsy

Wang Jin-gang, Yin Zhong-min, Wen Hua   

  1. Department of Neurosurgery, the 463 Hospital of Chinese PLA, Shenyang  110042, Liaoning Province, China
  • Received:2011-04-06 Revised:2011-05-09 Online:2011-06-04 Published:2011-06-04
  • About author:Wang Jin-gang★, Master, Attending physician, Department of Neurosurgery, the 463 Hospital of Chinese PLA, Shenyang 110042, Liaoning Province, China windyduan@tom.com

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Abstract:

BACKGROUND: Stem cells under appropriate conditions can differentiate into neurons, astrocytes and oligodendrocytes, which may radically improve neurons loss and glial cell degeneration in cerebral palsy children, thus to improve brain function in children.
OBJECTIVE: To retrospectively analyze the effects of stem cells from different sources on cerebral palsy children.
METHODS: The first author searched PubMed and Wanfang databases (1992/2011) for articles concerning therapies for cerebral palsy and stem cells from different sources for cerebral palsy.
RESULTS AND CONCLUSION: Neural stem cells for animal nerve injury repair have been a reported, but the clinical application of neural stem cells is still in clinical trials. Although embryonic, bone marrow blood, fetal cord blood, umbilical cord-derived stem cells have been applied to child cerebral palsy in some hospitals and a preliminary efficacy has been obtained, the specific evaluation criteria and long-term effects remain to be further studied.

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