Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (8): 1515-1518.doi: 10.3969/j.issn.1673-8225.2011.08.045

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Analysis of bone cement leakage in the percutaneous vertebroplasty in 22 of 102 cases

Peng Xiao-zhong, Chen Ming, Wu Zhen-guo, Yang Zhi-xian, Wei Han-yu, Lei Cheng-gang, Huang Zhan-zhu, Zhu Cheng-ming   

  1. Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou  545005, Guangxi Zhuang Autonomous Region, China
  • Received:2010-08-10 Revised:2010-10-23 Online:2011-02-19 Published:2011-02-19
  • Contact: Chen Ming, Doctor, Attending physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China
  • About author:Peng Xiao-zhong, Associate chief physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China nxcnn@163.com

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Abstract:

BACKGROUND: Bone cement has some traits of liquidity due to a higher proportion of leakage in the treatment of percutaneous vertebroplasty (PVP). How to minimize the probability of bone cement leakage in clinical work and prevent serious complications are hot issues of concern to scholars.
OBJECTIVE: To review bone cement leakage after percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fracture, and to summarize prevention and cure measures of bone cement leakage.
METHODS: Osteoporosis vertebral compression fractures in 131 centrums of 102 cases were treated with PVP. Injured centrum was located under the X-ray machine perspective, through the unilateral pedicle of vertebral arch to centrum 1/3 of before and middle was injected with bone cement to fill, diffusion satisfaction 3-5 minutes, the transfixion pin was pulled out. The degree of pain relief and bone cement leakage in patients were observed.
RESULTS AND CONCLUSION: A total of 90 cases with the pain completely disappeared, 8 cases with the pain significantly reduced, 4 cases with the pain reduced, without patients with exacerbation of pain. A total of 22 cases with bone cement leakage in surgery, including 3 cases of leakage in the spinal canal, without symptoms of acute spinal cord compression. 5 cases exhibited leakage under and around the anterior longitudinal ligament, without significant symptoms of major vascular erosion. 4 cases exhibit leakage around the nerve root canal, with irritative symptoms of unilateral nerve root and radioactive pain of unilateral lower limb. Patients were treated with dehydration, dexamethasone, and nerve nutrition, and then were relieved after the treatment of bed rest. 6 cases of leakage to peripheral vertebral, there was no neurological symptom. 1 case showed pulmonary punctate cement leakage, with no significant respiratory symptoms. 3 cases of leakage along the paravertebral vein spread from around the first and lower vertebral, there was no neurological symptom. There was no rejection in polymethacrylic acid bone cement in vivo. The results showed that PVP treatment of osteoporosis vertebral compression fractures has good effect, but with a higher incidences of cement leakage, surgical indications are need to be strictly controlled to reduce the incidences of bone cement leakage.

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