Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (8): 1487-1490.doi: 10.3969/j.issn.1673-8225.2011.08.038

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Reparation of meniscus sports injury with biomaterial

Li Xiao-yan   

  1. Physical Fitness Center, Institute of Physical Education, Henan Polytechnic University, Jiaozuo  454000, Henan Province, China
  • Received:2010-11-16 Revised:2010-12-16 Online:2011-02-19 Published:2011-02-19
  • About author:Li Xiao-yan★, Master, Lecturer, Physical Fitness Center, Institute of Physical Education, Henan Polytechnic University, Jiaozuo 454000, Henan Province, China sqh@hpu.edu.cn

Abstract:

BACKGROUND: The method of healing and rehabilitation using artificial biomaterial intervention after cartilage injury has been matured and diversified, and provides a new research direction for rehabilitation of meniscus.
OBJECTIVE: To explore the mechanism of meniscus sports injury, and to analyze the effect of biomaterial on injury repair of meniscus.
METHODS: PubMed database and CNKI database from 1990 to 2010 were retrieved by the first author. The articles related with meniscus injury, treatment of artificial materials were selected.
RESULTS AND CONCLUSION: Due to artificial biomaterial and compatibility of human, shape matching, adhesion, toughness, strength, etc. in the progress of specific practice and operation must be considered. The selection of ideal implant is more difficult.  At present reparation of meniscu with more biomaterials, including hyaluronic acid, collagen, gelatin, polyglycolic acid (PGA), polylactic acid, calcium polyphosphate (CPP), nonassimilable politef, carbon fiber polymer, etc. The stem cells were directionally induced or modified by transforming growth factor β1 gene. By regulating the growth and differentiation of multiple cells, bone marrow mesenchymal stem cells were differentiated into chondrocyte and inoculated in biological scaffolds, provided a new research direction for the injury and rehabilitation of meniscu.

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