Abstract:

OBJECTIVE: To summarize the clinical application progress of cruciate ligament reconstruction using LARS artificial ligament.
METHODS: PubMed database (2001-01/2010-05) and CNKI database (2001-01/2010-05) were searched using “LARS, artificial ligament, cruciate ligament, reconstruction” in English and in Chinese as the keywords. The language was limited to English and Chinese. A total of 205 articles were firstly collected, and 20 related studies were analyzed.
RESULTS: Currently used tissue engineered artificial ligament can be divided into natural and synthetic polymeric materials, including collagen, fibroin, lactic acid alcohol copolymer, and poly-L-lactic acid. These materials exhibit excellent biocompatibility, can promote cell adhesion, growth, secretion, and are gradually biodegradable. The major cause of injury of cruciate ligament is sports injury or traffic accident. In order to restore its function, surgical reconstruction is mainly adopted. The clinical results suggest that the reconstruction of cruciate ligament with LARS artificial ligament can accelerate rehabilitation and recover stabilization of knee joint, resulting in satisfactory functional recovery.
CONCLUSION: The LARS artificial ligament leads to good and rapid reconstruction. It seems to be an ideal graft material and is an effective treatment for athletes to resume high physical activity.