Abstract:

OBJECTIVE: Coronary stents include bare metal stents, drug-eluting stents, biodegradable stents and new types of stents such as radioactive stents, vein-covered stents and gene stents. How to choose the appropriate stent to achieve the best therapeutic effect is the medical research focus.
OBJECTIVE: To describe the clinical application of coronary stents, and to investigate the treatment effect of coronary stent implantation.
METHODS: Using “coronary stents, bare metal stents, drug eluting stents, biodegradable stent, cardiovascular new stent, blood coagulation system, inflammatory response” in Chinese as the key words, a computer search was performed in Chinese Journal Full-text Database (CNKI: 2002/2010). Meta analysis and reproducible study were excluded. A total of 27 articles were screened out, focusing on the coronary stent types, research progress and their biocompatibility, blood coagulation system changes after implantation of coronary stents, and inflammation reaction after coronary stents implantation.
RESULTS:  ① No matter bare metal stents, drug-eluting stents, biodegradable stents or new stents, the cardiovascular stents are modified in order to improve the biocompatibility and biomechanical properties. ② The biocompatibility of cardiovascular stents is a complex process, blood compatibility and tissue compatibility are two basic compositions for the assessment of the biocompatibility. ③ The mechanical properties of cardiovascular stents analyzed using finite element analysis can provide useful help for the optimal design.
CONCLUSION: The present cardiovascular stents have not completely solved the biocompatible problem, an ideal cardiovascular stent deserves further development and research.