Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (17): 3139-3142.doi: 10.3969/j.issn.1673-8225.2010.17.025

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Logistic regression analysis of risk factors for lumbar disc herniation in adolescents in Jinzhou city

Wang Yan-song, Mei Xi-fan   

  1. Department of Orthopaedics, First Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
  • Online:2010-04-23 Published:2010-04-23
  • About author:Wang Yan-song☆, Studying for doctorate, Physician, Department of Orthopaedics, First Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China wys990709@126.com

Abstract:

BACKGROUND: The pathogenesis and risk factors for lumbar disc herniation are significantly different between adults and teenagers. Previous studies seldomly refer to risk factors for lumbar disc herniation in adolescents by using logistic regression analysis.
OBJECTIVE: To investigate the risk factors for lumbar disc herniation in adolescents in Jinzhou by using logistic regression analysis.
METHODS: A total of 94 patients with lumbar disc herniation, including 56 males and 38 females, aging 9-18 years, were considered as the experimental group. A total of 100 patients suffering from other diseases were considered as the control group. Logistic regression analysis was employed to analyze risk factors for lumbar disc herniation onset, suggesting that OR >1 was taken as the risk factor for lumbar disc herniation, whereas OR <1 as the protective factor for lumbar disc herniation.
RESULTS AND CONCLUSION: All the 194 patients were involved in the final analysis. The result of logistic regression analysis showed that compared with control groups, the patients with lumbar disc herniation were statistically associated with familial predisposition (OR = 6.427, P = 0.015), trauma (OR = 17.196, P = 0.011), congenital malformations (OR = 31.429, P = 0.002), and over-exercise (OR = 12.644, P = 0.027). Trauma, congenital malformations, familial predisposition, and over-exercise were the risk factors for lumbar disc herniation in children and adolescents in Jinzhou. So it is necessary to implement a comprehensive prevention program, such as lifestyle and dietary habit modification, and proper activity.

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