Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (3): 517-520.doi: 10.3969/j.issn.1673-8225.2010.03.033

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Renal toxicity of dental porcelain crown containing Ni-Cr alloy: Theoretical study and clinical verification

Fan Can-can, Ning Jing, Meng Song, Li Ying-long, Peng Peng, Liu Bin   

  1. Stomatology Hospital of Lanzhou University, Lanzhou  730000, Gansu Province, China
  • Online:2010-01-15 Published:2010-01-15
  • Contact: Liu Bin, Doctor, Professor, Stomatology Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China liubkq@lzu.edu.cn
  • About author:Fan Can-can, Stomatology Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China Fancc07@lzu.cn
  • Supported by:

    Innovation and Pioneering Activities of Lanzhou University, No. 2009-141*; Medical Foundation of Lanzhou University, No. LZUYX200625*

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Abstract:

BACKGROUND: Dental porcelain crown containing Ni-Cr alloy has been widely used in modern dentistry. The dispute of its safety is limited in oral cavity and neighbor tissues, however, the relevance between Ni-Cr alloy and systemic disease, such as nephridium toxicosis, are poorly understood.
OBJECTIVE: To analyze the possibility of Ni-Cr porcelain crown resulted nephropathy and to explore its long-term clinical safety.
METHODS: Databases of VIP, CNKI, Wanfang, CBMdisc, Biosis Previews and BioOne were researched by computer with key words of “nickle chromium alloy, porcelain crown, nephridium toxicosis” both in Chinese and English. Literatures concerning Ni-Cr porcelain crown and toxicity of related metal ion were included, repetitive research was excluded.
RESULTS AND CONCLUSION: By consulting literatures, the possibility of erosion and release of heavy metal ion lead to nephridium toxicosis were analyzed with following aspects: effects of Ni-Cr alloy corrosivity and its accumulation on oral cavity or systemic disease; direct toxicity of released metal ions from Ni-Cr alloy and susceptivity of nephridium toxicosis; and the possible ways for renal damage resulted by Ni-Cr ion. This study can provide a basis for the further research concerning security of dental porcelain crown containing Ni-Cr alloy.

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