Chinese Journal of Tissue Engineering Research ›› 2025, Vol. 29 ›› Issue (27): 5862-5868.doi: 10.12307/2025.831

Previous Articles     Next Articles

Effects of unilateral biportal endoscopic transforaminal lumbar interbody fusion on paraspinal muscles

Wang Qianliang, Zhang Qianzhongyi, Peng Yujian, Yan Jun   

  1. Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China
  • Received:2024-05-28 Accepted:2024-08-21 Online:2025-09-28 Published:2025-03-06
  • Contact: Yan Jun, MD, Chief physician, Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China
  • About author:Wang Qianliang, MS, Attending physician, Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China
  • Supported by:
    National Natural Science Foundation of China, No. 81971036 (to YJ)

Abstract: BACKGROUND: With the development of unilateral biportal endoscopic technology, endoscopic lumbar fusion surgery has become an increasingly popular development trend in spinal surgery. Unilateral biportal endoscopic transforaminal lumbar interbody fusion shows significant advantages for preserving paravertebral muscle and reducing intraoperative bleeding in spinal stenosis and lumbar spondylolisthesis in the lumbar spine with degenerative changes. 
OBJECTIVE: To compare the effects of unilateral biportal endoscopic lumbar interbody fusion and traditional open transluminal lumbar interbody fusion on paraspinal muscles. 
METHODS: A retrospective analysis was conducted on the clinical data of 60 patients who visited the Department of Spine Surgery, Second Affiliated Hospital of Soochow University from October 2019 to November 2022 and underwent single segment unilateral decompression fusion. They were divided into two groups according to different surgical procedures. Group A received unilateral biportal endoscopic lumbar interbody fusion. Group B received traditional open transluminal lumbar interbody fusion. All patients underwent magnetic resonance imaging examination before and 3 months after surgery. Basic patient information, last follow-up time, magnetic resonance imaging images, visual analog scale scores for lower back and leg pain, and Oswestry Disability Index were collected.  
RESULTS AND CONCLUSION: (1) Three months after surgery, the cross-sectional area of the bilateral multifidus muscle in group A was significantly larger than that of group B (P < 0.05), and the degree of fat infiltration was lower (P < 0.01). (2) There was no significant difference in the cross-sectional area and degree of fat infiltration of bilateral erector spinae muscles between the two groups 3 months after surgery (P > 0.05). (3) It is concluded that unilateral biportal endoscopic lumbar interbody fusion is more effective than traditional open transluminal lumbar interbody fusion in protecting multifidus muscle, reducing multifidus muscle atrophy and fat infiltration. Both surgical methods did not have a significant impact on the erector spine muscle.

Key words: unilateral biportal endoscopy, lumbar interbody fusion through intervertebral foramen, lumbar disc herniation, paraspinal muscle injury, multifidus muscle, magnetic resonance imaging, pain, orthopedic implant 

CLC Number: