Chinese Journal of Tissue Engineering Research ›› 2025, Vol. 29 ›› Issue (4): 686-691.doi: 10.12307/2025.256

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Infiltration resin combined with whitening technique on micro-cracked dental fluorosis

Zhang Wenyi1, Yin Zhao2, Zhang Jian3   

  1. 1Department of Prosthodontics, 3Department of Oral and Maxillofacial Surgery, Stomatology Hospital, Tianjin Medical University, Tianjin 300070, China; 2No. 4 People’s Hospital of Hengshui, Hengshui 053000, Hebei Province, China
  • Received:2023-07-07 Accepted:2024-01-31 Online:2025-02-08 Published:2024-05-29
  • Contact: Zhang Wenyi, MD, Associate chief physician, Department of Prosthodontics, Stomatology Hospital, Tianjin Medical University, Tianjin 300070, China
  • About author:Yin Zhao, Master, Junior physician, No. 4 People’s Hospital of Hengshui, Hengshui 053000, Hebei Province, China Zhang Wenyi and Yin Zhao contributed equally to this article.
  • Supported by:
    a grant from Stomatology Hospital of Tianjin Medical University Project, No. 2020YKY05 (to ZWY); Tianjin Key Medical Discipline Construction Project, No. TJYXZDXK-038A

Abstract: BACKGROUND: Micro-abrasion, at-home whitening combined with infiltration resin have a good effect on dental fluorosis, but the effect of this method on micro-cracks in dental fluorosis is still unclear. 
OBJECTIVE: To explore the effect of micro-abrasion, at-home whitening combined with infiltration resin on micro-cracked dental fluorosis.
METHODS: (1) Clinical research: A total of 23 patients with micro-cracked dental fluorosis, including 255 micro-cracked dental fluorosis, were selected from July 2020 to March 2021 in the Department of Prosthodontics, Stomatology Hospital, Tianjin Medical University. All of them received combined treatment of tooth micro-abrasion, at-home whitening and infiltration resin. The tooth color, tooth sensitivity, and tooth pain threshold were compared before treatment and 1 week and 1 month after treatment. (2) In vitro experiment: 60 teeth with fluorosis with at least one crack on the tooth surface were collected and randomly divided into three groups for treatment. The control group was treated without any treatment. The whitening group was treated with micro-abrasion and at-home whitening, and the combined group was treated with micro-abrasion, at-home whitening, and infiltration resin, with 20 teeth in each group. The microhardness of the three groups of teeth samples after treatment was measured.
RESULTS AND CONCLUSION: (1) Clinical study: 6 months after treatment, among 255 teeth with micro-cracked dental fluorosis, whitening treatment for 207 teeth was significantly effective and whitening treatment for 48 teeth was effective, and the overall treatment efficiency was 100%. With the extension of treatment time, the proportion of moderate and severe dental sensitivity showed a decreasing trend. At 6 months after treatment, 255 teeth with dental fluorosis had no severe sensitivity, 15 with moderate sensitivity, 125 with mild sensitivity, and 115 with no sensitivity, and the difference was significant compared with the sensitivity before treatment (P < 0.05). There was no significant difference in the threshold of tooth pain before treatment and 1 week and 6 months after treatment (P > 0.05). (2) In vitro experiment: The tooth microhardness of the whitening group was lower than that of the control group and the combined group (P < 0.05), but there was no significant difference between the control group and the combined group (P > 0.05). (3) The results show that the methods of micro-abrasion, at-home whitening combined with infiltration resin have good clinical efficacy in the treatment of micro-cracked dental fluorosis.

Key words: dental fluorosis, cracks infil, tration resin, teeth whitening, therapeutic effect, micro-hardness

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