Abstract:

BACKGROUND: Prosthesis loose appeared after artificial total hip replacement. To understand the factors that affect stability of artificial total hip joint is necessary for elevating the curative effect of artificial total hip replacement.
OBJECTIVE: To summarize latest research progress of influential factors for stability of artificial total hip replacement, and to further understand the stability of artificial total hip joint.
METHODS: We retrieved China National Knowledge Infrastructure (1997-01/2010-12) for articles addressing sterile prosthesis loose after artificial total hip replacement. The key words were “artificial joint, replacement, stability”. A total of 98 articles were retrieved, and 30 articles were included in accordance with inclusion criteria.
RESULTS AND CONCLUSION: Influential factor and pathogenesis of the stability of artificial total hip replacement are complicated. The major factor is mechanics, followed by biology. Their effects lead to bone resorption, osteolysis, prosthesis loose and bone destruction. The process is strongly associated with the participation of many cytokines. We can prevent and cure the influential factors for the stability of artificial total hip joint from the aspects as follows: joint material, place angle, inhibition of worn particle motion, promotion of osteogenesis, and inhibition of bone resorption.