Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (34): 6417-6420.doi: 10.3969/j.issn.1673-8225.2010.34.036

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In vitro degradation of absorbable sutures and their clinical application in gynecology and obstetrics

Ye Li-ping, Cheng Gui-ping, Zhang Jin   

  1. Department of Gynecology and Obstetrics, People’s Hospital of Liaoning Province, Shenyang   110016, Liaoning Province, China
  • Online:2010-08-20 Published:2010-08-20
  • About author:Ye Li-ping, Associate chief nurse, Department of Gynecology and Obstetrics, People’s Hospital of Liaoning Province, Shenyang 110016, Liaoning Province, China lipingye2003@yahoo.com.cn

Abstract:

OBJECTIVE: To investigate the application of absorbable sutures in obstetrics and gynecology.
METHODS: A computer search was performed by the first author in VIP database (http://www.cqvip.com/) for articles abiout the absorbable sutures applied in surgical nursing of obstetrics and gynecology, using the key words “absorbable sutures; obstetrics and gynecology; care; biological materials”. Repeated researches were excluded. Totally 54 literatures were primarily screened out, according to inclusion criteria, 18 of them were involved in further summary.
RESULTS: With the transformation of medical model and increasing requirement of people for quality of life, absorbable suture as a kind of biomaterials, has been widely applied in surgery due to its excellent biocompatibility and mechanical strength, particularly have a very important clinical significance and long-term results for obstetric and gynecological surgery patients. Such sutures can reduce surgical time and postoperative infection rates, promote postoperative recovery and decrease the foreign body to wound, relieve pain for individual patients, also have reflected a significance on departments and hospital management. Suture plays a very important guide role for obstetric and gynecological surgery. In addition, effective analysis for its degradation products shows that, clinicians should focus on horizontal comparison among a variety of sutures, its degradation security in vivo still need to concluded integrating with in vivo degradation test and toxicity kinetics studies, so as to ensure its clinical effect.
CONCLUSION: The absorbable sutures as a biomaterial have achieved an increasingly application in surgery due to its good biological compatibility and mechanical strength. As for obstetrics and gynecology, such as cesarean section, episiotomy and perineal tears sutures, the clinicians and patients tend to use absorbable suture for surgical suture and effective suture of the wound.

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