Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (34): 6413-6416.doi: 10.3969/j.issn.1673-8225.2010.34.035

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Material characteristics of vascular stent and its complications after implantation

Ma Ming-hui   

  1. Department of Neurology (First Ward), Shenyang Fifth People’s Hospital, Shenyang   110023, Liaoning Province, China
  • Online:2010-08-20 Published:2010-08-20
  • About author:Ma Ming-hui★, Studying for master’s degree, Physician, Department of Neurology (First Ward), Shenyang Fifth People’s Hospital, Shenyang 110023, Liaoning Province, China mhyl2009@hotmail.com

Abstract:

OBJECTIVE: To investigate the cerebral vascular stent material characteristics and its treatment of cerebral vascular disease, the application effect of stent complications causes.
METHODS: First author conducted an online retrieval of Wanfang database (http://www.wanfangdata.com.cn/) and Pubmed database (http://www. Ncbi.nlm.nih.gov/pubmed/) for articles related with the material characteristics of cerebrovascular stent materials and complications after implantation, published between January 1999 and December 2009, using the key words of “intravascular stent, cerebrovascular disease, complications” in Chinese. Totally 21 articles were screened into the evaluation.
RESULTS: The cerebrovascular stent complications include carotid sinus response, high-perfusion syndrome, cerebral vasospasm, thrombosis, restenosis and so on. In a variety of cerebrovascular stents, metal stents are prone to promote thrombosis; polymer stents have better compatibility with vessel wall than metal stents, thus preventing late neointimal proliferation; coated stent can coat metal stent surface with a special coating technology, inhibiting platelet aggregation; drug stents can achieve high concentrations of drugs sustained release after implantation, the drugs can reach effective therapeutic concentrations in target site and effectively prevent restenosis after implantation. The incidence of complications after stenting is difficult to completely eradicate, but they should be avoided, it is suggested to select positive solutions for stent cases, improve the operator’s proficiency, correct bad operation habits, better the patient’s understanding of the complications, strictly perform perioperative management, timely and correctly give treatment of the complications to avoid serious consequences.
CONCLUSION: The treatment of cerebral vascular stent implantation can be considered as one of the main treatments for cerebrovascular disease, during treatment, adequate preparation, appropriate stent, and strictly follow of the indications are required to avoid complications according to different clinical symptoms.

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