Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (29): 5325-5328.doi: 10.3969/j.issn.1673-8225.2010.29.002

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Preparation and property of closed dressing intelligent scaffolds

Tang Na1, Cai Wen-zhi2, Deng Ling3, Li Shu-juan1, Wang Xiao-juan1, Li Chao1   

  1. 1 Shenzhen Fourth People’s Hospital, Shenzhen   518033, Guangdong Province, China; 2 Nursing College of Southern Medical University, Guangzhou  510515; Guangdong Province, China; 3 Nanfang Hospital, Southern Medical University, Guangzhou   510515, Guangdong Province, China
  • Online:2010-07-16 Published:2010-07-16
  • About author: Tang Na★, Studying for master’s degree, Nurse-in-charge, Shenzhen Fourth People’s Hospital, Shenzhen 518033, Guangdong Province, China prettymedictn@yahoo.com.cn
  • Supported by:

    Guangdong Provincial Natural Science Foundation, No. 2004B30101019*

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Abstract:

BACKGROUND: In recent years, the wound dressing research has developed quickly, but few reports the closed dressings prepared by traditional Chinese medicine combined with polymer composite, the efficacy of existing wound dressings is limited and not suitable for all wounds.
OBJECTIVE: To prepare closed dressing scaffolds loading traditional Chinese medicine, and to determine their properties.
METHODS: Firstly the chitosan, gelatin and polyvinyl alcohol were mixed, while the above materials were additionally mixed with sodium alginate. The scaffolds were prepared by mixing, precooling and freeze drying. The properties of the enclosed dressing scaffolds was evaluated by water absorption, moisture content, relative moisture retention, permeability, porosity, and scaffold appearance.
RESULTS AND CONCLUSION: Water absorption, moisture content, relative moisture retention and porosity of the mixture of chitosan, gelatin and polyvinyl alcohol were significantly better than those of the mixture containing chitosan, gelatin, polyvinyl alcohol and sodium alginate (P < 0.05). Chitosan, gelatin and polyvinyl alcohol are suitable to be used as closed dressing intelligent scaffolds.

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