Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (16): 2484-2488.doi: 10.3969/j.issn.2095-4344.2015.16.005

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Percutaneous kyphoplasty with bone cement injection for treatment of spinal metastases: changes of spinal stability and pain

Liu Yong1, Xia Bo2, Li Xin-fu1   

  1. 1Feicheng Mining Industry Central Hospital, Taian 271608, Shandong Province, China; 2Taian Central Hospital, Taian 271000, Shandong Province, Chins
  • Received:2015-02-11 Online:2015-04-16 Published:2015-04-16
  • Contact: Li Xin-fu, Attending physician, Feicheng Mining Industry Central Hospital, Taian 271608, Shandong Province, China. Corresponding author: Xia Bo, Attending physician, Taian Central Hospital, Taian 271000, Shandong Province, Chins
  • About author:Liu Yong, Attending physician, Feicheng Mining Industry Central Hospital, Taian 271608, Shandong Province, China

Abstract:

BACKGROUND: Patients with spinal metastases may appear different degrees of pain and abnormal spinal stability, and can be treated with percutaneous balloon kyphoplasty combined with bone cement implantation.
OBJECTIVE: To explore the effect of percutaneous balloon kyphoplasty with bone cement implantation on spinal stability and pain in patients with spinal metastases.
METHODS: Twenty-three patients with metastatic spinal tumor were treated with percutaneous balloon dilatation kyphoplasty with polymethyl methacrylate bone cement. There were 10 females and 13 males, and their age ranged from 23 to 71 years. The visual analogue scale score, anterior and posterior edge height of vertebral body, quality of life, and motor function score of patients were observed before and after treatment.
RESULTS AND CONCLUSION: Compared with before treatment, the visual analogue scale score and motor function score were significantly decreased, while anterior and posterior edge height of vertebral body were
significantly increased in 23 patients at 24 hours after treatment (P < 0.05). After 12 months of follow-up, no case appeared to have spinal nerve root damage, serious adverse reactions and bone cement embolism. The patient’s quality of life was significantly improved, compared with before treatment (P < 0.05). Experimental findings indicate that percutaneous balloon dilatation kyphoplasty with polymethyl methacrylate bone cement can significantly improve the spinal stability, relieve the degree of pain, and exert exact effects in treatment of spinal metastases.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words: pine, Methylmethacrylates, Vertebroplasty

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