A meta-analysis of ultrasonic therapy on relieving pain of knee osteoarthritis patients

doi:10.3969/j.issn.2095-4344.2014.33.026

Abstract

Abstract:

BACKGROUND: Ultrasonic therapy is one of several physical therapy modalities suggested for the management of pain and loss of function due to osteoarthritis. However, its effectiveness still remains controversial in the previous studies.
OBJECTIVE: To analyze the effect of ultrasonic therapy for the treatment of relieving knee osteoarthritis pain.
METHODS: A retrieval of Pubmed, Ovid/Medline, Ovid/EMBASE, and Cochranee database was performed. The relevant literatures were manually retrieved. The retrieval deadline was set on March 31, 2014. Randomized controlled trials on ultrasonic therapy of knee osteoarthritis were collected.
RESULTS AND CONCLUSION: A total of eight studies of meta-analysis were accumulated. Among them, six studies adopted visual analog scale and Western Ontario and McMaster Universities Arthritis Index, one study adopted visual analog scale only, and one study adopted Western Ontario and McMaster Universities Arthritis Index. Then the Western Ontario and McMaster Universities Arthritis Index scores were transformed into visual analog scale scores for data analysis. There was a statistical difference between the groups in the visual analog scale pain score (standardized standard deviation: -0.51; 95% confidence interval: -0.68, -0.33; P=0.05). Ultrasonic therapy is an effective method for knee osteoarthritis pain.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: ultrasonic therapy, osteoarthritis, knee, pain

CLC Number:

R318

Yang Ye, Zeng Chao, Deng Zhen-han, Zhang Yi, Li Yu-sheng, Li Hui, Yang Tuo, Lei Guang-hua. A meta-analysis of ultrasonic therapy on relieving pain of knee osteoarthritis patients[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(33): 5396-5401.

Figures/Tables 5

References

[1]Zhang Y, Jordan JM. Epidemiology of osteoarthritis. Clin Geriatr Med.2010;26(3):355-369.
[2]Quintana JM,Arostegui I,Escobar A,et al.Prevalence of knee and hip osteoarthritis and the appropriateness of joint replacement in an older population. Arch Intern Med. 2008; 168(14):1576-1584.
[3]Zeng QY, Chen R, Darmawan J,et al. Rheumatic diseases in China. Arthritis Res Ther.2008;10(1):R17.
[4]Litwic A,Edwards MH,Dennison EM,et al.Epidemiology and burden of osteoarthritis. Br Med Bull.2013;105:185-199.
[5]Iversen MD.Rehabilitation interventions for pain and disability in osteoarthritis. Am J Nurs.2012;112(3 Suppl 1):S32-7.
[6]Rand SE, Goerlich C, Marchand K,et al. The physical therapy prescription. Am Fam Physician.2007;76(11):1661-1666.
[7]Baker KG, Robertson VJ,Duck FA. A review of therapeutic ultrasound: biophysical effects. Phys Ther.2001;81(7): 1351-1358.
[8]Dalecki D. Mechanical bioeffects of ultrasound. Annu Rev Biomed Eng.2004;6:229-248.
[9]Huang MH, Ding HJ, Chai CY,et al.Effects of sonication on articular cartilage in experimental osteoarthritis. J Rheumatol. 1997;24(10):1978-1984.
[10]Huang MH, Yang RC, Ding HJ,et al. Ultrasound effect on level of stress proteins and arthritic histology in experimental arthritis. Arch Phys Med Rehabil. 1999;80(5):551-556.
[11]Parvizi J, Wu CC, Lewallen DG,et al. Low-intensity ultrasound stimulates proteoglycan synthesis in rat chondrocytes by increasing aggrecan gene expression. J Orthop Res. 1999; 17(4):488-494.
[12]Cook SD, Salkeld SL, Popich-Patron LS,et al. Improved cartilage repair after treatment with low-intensity pulsed ultrasound. Clin Orthop Relat Res.2001;(391 Suppl):S231-43.
[13]Cui JH, Park K, Park SR,et al.Effects of low-intensity ultrasound on chondrogenic differentiation of mesenchymal stem cells embedded in polyglycolic acid: an in vivo study. Tissue Eng.2006;12(1):75-82.
[14]Min BH, Woo JI, Cho HS,et al. Effects of low-intensity ultrasound (LIUS) stimulation on human cartilage explants. Scand J Rheumatol.2006;35(4):305-311.
[15]Choi BH, Woo JI, Min BH,et al.Low-intensity ultrasound stimulates the viability and matrix gene expression of human articular chondrocytes in alginate bead culture. J Biomed Mater Res A.2006;79(4):858-864.
[16]Cook SD, Salkeld SL, Patron LP, et al. The effect of low- intensity pulsed ultrasound on autologous osteochondral plugs in a canine model. Am J Sports Med. 2008;36(9):1733-1741.
[17]Welch V,Brosseau L,Peterson J,et al.Therapeutic ultrasound for osteoarthritis of the knee. Cochrane Database Syst Rev. 2001;(3):CD003132.
[18]Rutjes AW,Nuesch E,Sterchi R,et al.Therapeutic ultrasound for osteoarthritis of the knee or hip. Cochrane Database Syst Rev.2010;(1):CD003132.
[19]McAlindon TE,Bannuru RR,Sullivan MC,et al.OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage.2014;22(3):363-388.
[20]van Tulder M, Furlan A, Bombardier C,et al.Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine (Phila Pa 1976). 2003; 28(12):1290-1299.
[21]Huang MH, Lin YS, Lee CL,et al. Use of ultrasound to increase effectiveness of isokinetic exercise for knee osteoarthritis. Arch Phys Med Rehabil.2005;86(8): 1545-1551.
[22]Huang MH, Yang RC, Lee CL,et al. Preliminary results of integrated therapy for patients with knee osteoarthritis. Arthritis Rheum.2005;53(6):812-820.
[23]Ozgonenel L, Aytekin E,Durmusoglu G.A double-blind trial of clinical effects of therapeutic ultrasound in knee osteoarthritis. Ultrasound Med Biol.2009;35(1):44-49.
[24]Tascioglu F,Kuzgun S,Armagan O,et al.Short-term effectiveness of ultrasound therapy in knee osteoarthritis. J Int Med Res.2010;38(4):1233-1242.
[25]Ulus Y, Tander B, Akyol Y,et al.Therapeutic ultrasound versus sham ultrasound for the management of patients with knee osteoarthritis: a randomized double-blind controlled clinical study. Int J Rheum Dis.2012;15(2):197-206.
[26]Cakir S, Hepguler S, Ozturk C,et al.Efficacy of Therapeutic Ultrasound for the Management of Knee Osteoarthritis: A Randomized, Controlled, and Double-Blind Study. Am J Phys Med Rehabil. 2014;93(5):405-412.
[27]Cetin N, Aytar A, Atalay A,et al. Comparing hot pack, short-wave diathermy, ultrasound, and TENS on isokinetic strength, pain, and functional status of women with osteoarthritic knees: a single-blind, randomized, controlled trial. Am J Phys Med Rehabil.2008;87(6): 443-451.
[28]Loyola-Sanchez A, Richardson J, Beattie KA,et al. Effect of low-intensity pulsed ultrasound on the cartilage repair in people with mild to moderate knee osteoarthritis: a double-blinded, randomized, placebo-controlled pilot study. Arch Phys Med Rehabil.2012;93(1):35-42.
[29]Zhang W,Nuki G, Moskowitz RW,et al.OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.Osteoarthritis Cartilage.2010;18(4):476-499.
[30]Loyola-Sanchez A,Richardson J,MacIntyre NJ. Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis. Osteoarthritis Cartilage. 2010;18(9):1117-1126.
[31]Falconer J, Hayes KW,Chang RW.Effect of ultrasound on mobility in osteoarthritis of the knee. A randomized clinical trial. Arthritis Care Res.1992;5(1):29-35.
[32]Stewart HG, Stratmeyer ME. An Overview Of Ultrasound: Theory, Measurement, Medical Applications, and Biological Effects. Washington, DC: Department of Health, Education, and Welfare; DHEW Publication.1982:82-8190.
[33]Love LA, Kremkau FW.Intracellular temperature distribution produced by ultrasound. J Accoust Soc Am.1980;67: 1045-1050.
[34]Srbely JZ, Dickey JP, Lowerison M,et al. Stimulation of myofascial trigger points with ultrasound induces segmental antinociceptive effects: a randomized controlled study. Pain. 2008;139(2):260-266.
[35]Knight CA, Rutledge CR, Cox ME,et al. Effect of superficial heat, deep heat, and active exercise warm-up on the extensibility of the plantar flexors. Phys Ther. 2001;81(6): 1206-1214.
[36]Loch EG, Fischer AB,Kuwert E.Effect of diagnostic and therapeutic intensities of ultrasonics on normal and malignant human cells in vitro. Am J Obstet Gynecol.1971;110(4): 457-460.
[37]Pizzarello DJ, Wolsky A, Becker MH,et al. A new approach to testing the effects of ultrasound on tissue growth and differentiation. Oncology.1975;31:226-232.
[38]Ross P, Edmonds PD.Ultrasound induced protein synthesis as a result of membrane damage. J Ultrasound Med.1983; 2(suppl):47.
[39]Webster DF, Pond JB, Dyson M,et al. The role of cavitation in the in vitro stimulation of protein synthesis in human fibroblasts by ultrasound. Ultrasound Med Biol.1978;4: 343-351.
[40]Anderson DW, Barrett JT. Depression of phagocytosis by ultrasound. Ultrasound Med Biol.1981;7:267-273.
[41]Fischell TA, Abbas MA, Grant GW,et al. Ultrasonic energy: effects on vascular function and integrity. Circulation. 1991; 84:1783-1795.
[42]Maxwell L, Collecutt T, Gledhill M,et al.The augmentation of leucocytes adhesion to endothelium by therapeutic ultrasound. Ultrasound Med Biol.1994;20:383-390.
[43]Steffen W, Cumberland D, Gaines P,et al. Catheter-delivered high intensity, low frequency ultrasound induces vasodilation in vivo. Eur Heart J.1994;15:369-376.
[44]Doan N, Reher P, Meghji S,et al. In vitro effects of therapeutic ultrasound on cell proliferation, protein synthesis and cytokine production by human fibroblasts, osteoblasts and monocytes. J Oral Maxillofac Surg.1999;57:409-419.
[45]Johns LD, Colloton PA, Neuenfeldt J. Effects of therapeutic ultrasound on T cell proliferation and IL-2 production. J Athl Train.1999;34(suppl):S24.
[46]Reher P, Doan N, Bradnock B, et al. Effect of ultrasound on the production of IL-8, basic FGF and VEGF. Cytokine.1999; 11: 416-423.
[47]Johns LD.Nonthermal effects of therapeutic ultrasound: the frequency resonance hypothesis. J Athl Train.2002;37(3): 293-299.
[48]Paul WD, Imig CJ.Temperature and blood flow studies after ultrasonic irradiation. Am J Phys Med.1955;34(2):370-375.