Abstract:

BACKGROUND: Artificial joint replacement or allogeneic bone fixation and bone substitute materials filling are common ways to repair bone defects in giant cell tumor of bone after curettage, so which one is more ideal?
OBJECTIVE: To understand the staging standard of giant cell tumors through access to Chinese and English literature about treatment for giant cell tumor of bone, and to compare different therapies, bone graft, bone cement filling and prosthesis.
METHODS: A computer based search of CNKI using keywords of “tumor-type prosthesis, giant cell tumor of bone, bone graft, bone cement” and Elsevier Science and Pringer-Link using keywords of “giant cell tumor of bone, therapy, tumor-type prosthesis” were performed to retrieve relevant articles. Totally 346 articles were retrieved, and finally 26 were included in result analysis.
RESULTS AND CONCLUSION: The traditional treatments for giant cell tumor have a higher recurrence rate. The bone graft may not be able to fill the entire bone cavity, bone cement materials cannot be easy to be fused with the host. Tumor-type prosthesis shows a good effect on giant cell tumor of bone, but it is still inadequate. However, special prosthesis joints can repair bone defects following giant cell tumor of bone according to individualized treatment needs, which is an effective and reliable surgical method as well as the main research direction for the future treatment of giant cell tumor of bone.