Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (45): 8520-8524.doi: 10.3969/j.issn.1673-8225.2011.45.036

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Adult stem cells and lung regeneration

Su Shen, Sun Hai-yan, Zhang Tong, Wu Li-jun, Yao Ji-rong   

  1. Department of Neurology, Beijing Shijitan Hospital of Capital Medical University, Beijing  100038, China
  • Received:2011-08-25 Revised:2011-09-21 Online:2011-11-05 Published:2011-11-05
  • Contact: Yao Ji-rong, Nurse in charge, Department of Neurology, Beijing Shijitan Hospital of Capital Medical University, Beijing 100038, China beijingshijitan@163.com
  • About author:Su Shen, Department of Neurology, Beijing Shijitan Hospital of Capital Medical University, Beijing 100038, China beijingshijitan@163.com
  • Supported by:

    the National Natural Science Foundation of China, No. 81100366*

Abstract:

BACKGROUND: Stem cells with active homing function and regulation has a great application prospect to lung regeneration due to the lung tissue with complex structure and long disease cycle.
OBJECTIVE: To overally understand the progress of adult stem cells in treatment of lung diseases and injury.
METHODS: The first author retrieved PuMed for articles about adult stem cells for lung injury published before 2011. Repetitive articles were excluded.
RESULTS AND CONCLUSION: Totally 135 articles were retrieved, and finally 50 articles were included in result analysis. Bone marrow-derived mesenchymal stem cells as the representative of adult stem cells have a strong multi-differentiation potential for the treatment of lung disease, which can involved in wound healing and tissue regeneration. However, the therapeutical mechanism and related influential factors need further studies.

CLC Number: