Abstract:

BACKGROUND: The precisely etiological factors and pathogenesis of knee osteoarthritis remain unclear.
OBJECTIVE: To analyze clinical manifestations of patients with knee osteoarthritis and to explore the influence factors of knee osteoarthritis.
METHODS: The general information, such as present illness, past history, physical examination, X-ray film inspection, disease diagnosis and laboratory tests were collected for 315 patients with knee osteoarthritis who were hospitalized in a hospital in Qingdao from July 2007 to November 2009. Statistical comparisons were performed Using SPSS 13.0 software with the χ2 test to analyze influence factors in patients with knee osteoarthritis.
RESULTS AND CONCLUSION: ①The percentage of left knee joint pain in patients with knee osteoarthritis was 21.6% and in right knee was 29.5%. The percentage of right knee pain was higher than in left knee (P < 0.01). The percentage of one knee joint pain in patients with knee osteoarthritis was 51.1% and in double knees was 48.9%. There were no statistically significant differences (P > 0.01). ②The detection rate of knee osteoarthritis in women was higher than in men (P< 0.01). The disease incidence was related to age in an increasing tendency with age. ③Compared with non-obesity population, the obesity population suffered a higher incidence of knee osteoarthritis (P< 0.01). There were no statistically significant differences in gender. ④A higher labor intensity in patient means more incidence of knee osteoarthritis. ⑤The detection rate of knee osteoarthritis in postmenopausal women was higher than pre-menopausal women (P < 0.05). The postmenopausal ages were 45-60-year (All subjects over 60 years had menopause). The results demonstrated that gender, age, body mass index, occupation (worker, housework), as well as genetic results are risk factors that cause knee osteoarthritis in the elderly, especially age, which is the highest risk factor.