Chinese Journal of Tissue Engineering Research

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Tendon allograft transplantation repairs Achilles tendon rupture

Tang Heng-tao, Wang Chuang-jian, Yan Xu, Zhang Chun-lin   

  1. Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou  450052, Henan Province, China
  • Received:2013-03-11 Revised:2013-03-24 Online:2013-07-30 Published:2013-07-30
  • About author:Tang Heng-tao☆, M.D., Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China tbh2005zzly@yahoo.com.cn

Abstract:

BACKGROUND: For the treatment of Achilles tendon rupture, peripheral ankle autologous tendon displacement is the traditional method in clinic, while the source of autologous tendon is limited, has damage to the donor site and has to pay with the normal power and stable structure. Allogenic tendon has the advantages of rich sources, easy to obtain, no damage to the normal structure of the host, and can maintain its original biological structure.
OBJECTIVE: To evaluate the clinical effect of tendon allograft transplantation on the repair of Achilles tendon rupture.
METHODS: Thirty cases of acute and old Achilles tendon rupture and four cases of chronic rupture with 2-5 cm deficiency were treated from August 2008 to June 2011. The cases were treated with tendon allograft transplantation, and short leg cast was used to fix the limb after transplantation. Functional exercises were commenced at 4 weeks after cast removal. The clinical treatment results were evaluated by Arner-lindholm criteria.
RESULTS AND CONCLUSION: The mean hospital stay was about 12.5 days. Twenty-five cases were followed-up for 1-3 years after transplantation and no rupture recurred. According to Arner-lindholm criteria, excellent was in 25 cases, good in 3 cases, fair in 2 cases, and the excellent and good rate was 92%. Ankle joint function was recovered to the normal level. Three cases had adhesion between Achilles tendon and adjacent tissue that had impact on the ankle dorsiflexion, and there was no significance decrease in foot pedal force. Two cases had rejection that healed after symptomatic treatment. One case had less flap margin necrosis and incision infection that healed after dressing and adjacent flap coverage. Incisions of all patients were healed at discharge. The results show that tendon allograft transplantation has satisfactory effect for reaping the Achilles tendon rupture which is a recommended treatment option. But the long-term effect needs further observation.

Key words: organ transplantation, tissue transplantation, Achilles tendon rupture, allograft, tendon, repair, suture, ligament, defect

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