Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (27): 4289-4293.doi: 10.12307/2021.184

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Titanium plate placement for internal fixation of slopes in children aged 1-6 years: digital morphological analysis of mechanical support

Li Kun, Li Zhijun, Zhang Shaojie, Gao Shang, Wang Xing, Sun Hao, He Yujie, Wang Haiyan, Cai Yongqiang, Xu Xuebin    

  1. 1Department of Human Anatomy, 2Digital Medical Center, 3Student Management Office, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia Autonomous Region, China
  • Received:2020-10-17 Revised:2020-10-21 Accepted:2020-12-14 Online:2021-09-28 Published:2021-04-10
  • Contact: Li Zhijun, Professor, Doctoral supervisor, Department of Human Anatomy, and Digital Medical Center, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia Autonomous Region, China Zhang Shaojie, Professor, Master’s supervisor, Department of Human Anatomy, Inner Mongolia Medical University, Hohhot 01000, Inner Mongolia Autonomous Region, China
  • About author:Li Kun, Master, Department of Human Anatomy, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia Autonomous Region, China Wang Xing, Doctoral candidate, Department of Human Anatomy, Inner Mongolia Medical University, Hohhot 010000, Inner Mongolia Autonomous Region, China
  • Supported by:
    the National Natural Science Foundation of China, No. 81860382 (to WX), No. 81860383 (to LZJ), No. 81660358 (to ZSJ); the Research and Innovation Fund for Postgraduates in Inner Mongolia Autonomous Region, No. S2018112010Z (to LK); the Talent Cultivation Project of Inner Mongolia Medical University, No. YCPY20200090, YCPY20200002 (to LK); the Laboratory Opening Project of Inner Mongolia Medical University, No. 2020ZN48 (to LK); the Innovation and Entrepreneurship Project of Inner Mongolia Medical University, No. 20201032001 (to LK); the Enlightenment Plan of Inner Mongolia Medical University, No. FYQMJH2020034 (to LK); the Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2020MS03061 (to WX), No. 2020LH08021 (to LZJ), No. 2019MS08017 (to ZSJ)  

Abstract: BACKGROUND: Occipital neck instability is caused by bone or soft tissue structural abnormalities or injuries. In clinical practice, patients with posterior or anterior upper cervical bone fractures in the occipital neck region need to undergo anterior skull slope internal fixation, which is currently used in adults. Up to now, there is no common developmental anatomy data (size and position of titanium plate for internal fixation) of children in this area at home and abroad for reference.
OBJECTIVE: To study the slope and adjacent anatomical structures of children aged 1-6 years, and to provide detailed information for placement of titanium plates for internal fixation of slopes.
METHODS:  The original cervical CT data of 110 children aged 1-6 years were divided into three groups: 1-2-year group (n=30), 3-4-year group (n=39) and 5-6-year group (n=41). Mimics software was used for three-dimensional reconstruction to measure the parameters such as the length of the extracranial slope, the length of the intracranial slope, the width of the bottom of the slope, and the distance between the pharyngeal tuberculum and the bottom of the slope.  
RESULTS AND CONCLUSION: (1) The mean slope of each parameter was on the rise along with the age growth. Differences in intracranial slope length, intracranial external adjustment pillow cartilage combined with distance from the bottom of the slope, slope bottom width, pharynx nodules from the bottom of the slope distance, and broken hole inside edge distance were significant among the three groups (P < 0.05). Slope top width was significantly different between 5-6-year group and the 1-2-year and 3-4-year groups (P < 0.05). The slope angle of cervical spine was not significantly different among the three groups (P > 0.05). (2) The dimensions of titanium plates for internal fixation placed on the slope were: the top width of titanium plate was 8 mm; the middle width was 19.1 mm; the bottom width was 26.9 mm; and the length was 23.7 mm in the 1-2-year group. The top width of titanium plate was 8.1 mm; the middle width was 20.6 mm; the bottom width was 31.3 mm; and the length was 26.5 mm in the 3-4-year group. The top width of titanium plate was 10.4 mm; the middle width was 22 mm; the bottom width was 37.3 mm; and the length was 28 mm in the 5-6-year group. (3) According to the analysis of slope area parameters, the sizes of titanium plates placed on slopes for children aged 1-6 years were obtained, which helped clinicians master the slope anatomical structure and improve the safety of titanium plates placed.

Key words: children, occipitoatlantoaxial complex, slope, titanium plate, spiral CT, developmental characteristics, internal fixation

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