Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (23): 3725-3733.doi: 10.12307/2021.046
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Huang Maomao, Hu Yue, Wang Binchuan, Zhang Chi, Xie Yujie, Wang Jianxiong, Wang Li, Xu Fangyuan
Received:
2020-04-16
Revised:
2020-04-22
Accepted:
2020-06-17
Online:
2021-08-18
Published:
2021-02-24
Contact:
Xu Fangyuan, Master, Chief physician, Department of Rehabilitation Medicine, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
About author:
Huang Maomao, Master, Physician, Department of Rehabilitation Medicine, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Supported by:
CLC Number:
Huang Maomao, Hu Yue, Wang Binchuan, Zhang Chi, Xie Yujie, Wang Jianxiong, Wang Li, Xu Fangyuan. Bibliometric and visual analysis of international literature addressing ischemic stroke rehabilitation in recent 10 years[J]. Chinese Journal of Tissue Engineering Research, 2021, 25(23): 3725-3733.
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2.1 全球科研产出及资金来源分析 从2010至2019年,缺血性脑卒中康复领域总共发表了3 098篇文章。图2显示了每年的发文数量。研究阶段可以分为2个阶段:第1阶段是2010至2017年即持续发展期,第2阶段是2017至2019年即平台期。第1阶段呈现出逐年增长的趋势,发文数量从2010年的175篇逐渐增多至2017年的442篇,平均每年增长33.75篇,增长率为11.57%;第2阶段呈现一个相对平稳状态,每年发文量在400篇上下波动,2019年发文数量为424篇。总共有2 865笔资金支持了该领域的研究。表1列出了前10位主要基金来源,都属于国家级机构或组织,大部分来源于发达国家。其中美国卫生及公共服务部、美国国立卫生研究院以及中国国家自然科学基金排名前3位。 "
2.2 期刊分析 在过去10年中,共有775个期刊发表了该领域的文献。表2列出了发文数量最多的10个期刊,发文量仅占24.56%。发文数量最多的前3个期刊分别是《Journal of Stroke Cerebrovascular》(150),《Stroke》(136)及《Archives of Physical Medicine and Rehabilitation》(96)。前10个期刊的影响因子(Impact Factor, IF)波动在1.646-6.046,IF < 2.000的有2个,IF=2.000-4.000的有6个,IF > 4.000的有2个,其中IF > 2.000的占了80%,最高的是《Stroke》(6.046)。上述期刊大部分都是该领域的专业期刊或活跃期刊。在775个期刊中,IF最高的前5个期刊分别是《Lancet》(59.102)、《JAMA》(51.273)、《Nature》(43.07)、《Nature Medicine》(30.641)以及《Lancet Neurology》(28.755)。 "
2.3 科研合作网络分析 82个国家/地区发表了有关该主题的文章,合作网络图见图3。图3A,B分别是国家/地区共现次数和中心性的网络图谱。图4A显示了爆发的4个国家,分别是德国、以色列、尼日利亚和伊朗。图5A揭示了国家/地区之间的合作:美国的合作伙伴是法国;中国与澳大利亚有合作;俄罗斯则与菲律宾、丹麦、巴西、爱尔兰等国家密切合作;与比利时合作的国家有德国、瑞士、荷兰、法国、俄罗斯等。表3列出了发文数量、共现次数、中心性排名前10的国家,按发文数量和共现次数排名前3的是美国、中国和加拿大,按中心性排名前3的是俄罗斯、比利时和法国。表4列出了发文数量最多的10个国家及其引用相关数据,引用次数最多的前3个国家是美国、中国、加拿大;平均引用次数最多的3个国家则是英国、德国和加拿大。 "
在过去10年的研究中,有4 015个研究机构发布了该领域的文章。表5,6列出了发文数量、共现次数以及中心性排名前10的机构及其引用数据。发表文章数量最多的前3个机构与共现次数最多的前3个机构相同,它们分别是多伦多大学、首都医科大学以及卡尔加里大学。被引次数最多的前3个机构是多伦多大学、卡尔加里大学和墨尔本大学。就中心性而言,排名前3的机构是爱丁堡大学、弗洛里神经科学与精神研究所以及哈佛医学院。机构之间的共现分析如图3C,D所示。爆发性检测显示一共有10个机构爆发,如图4B所示。按爆发强度排序,前3的机构是查理特大学(2011至2013年)、特拉维夫大学(2010至2012年)、格拉斯哥喀里多尼亚大学(2012至2013年)。如图5B所示,多伦多大学的重要合作伙伴包括森尼布鲁克健康科学中心、蒙特利尔大学、多伦多康复中心、英属哥伦比亚大学等;首都医科大学与浙江大学、武汉大学、四川大学、北京大学、清华大学等进行了密切合作;与爱丁堡大学密切合作的机构有格拉斯哥大学、格拉斯哥喀里多尼亚大学、伊利诺斯州大学、布莱梅大学、堪萨斯大学、麦克马斯特大学、伯明翰大学等10多个机构;与弗洛里神经科学与精神研究所合作的有爱丁堡大学、香港理工大学、拉筹伯大学。 "
一共有14 676位作者参与关于缺血性脑卒中康复领域的4 188篇文章。表7,8列出了发文数量和共现次数最多的10个作者。发文数量最多的前3个作者是Kirton A(25)、Schwamm LH(23)和Bernhardt J(20);引用次数最多的前3个作者则分别是Bernhardt J(903)、Kwakkel G(677)和Cramer SC(588);共现次数最多的前3位是Kirton A(23)、Schwamm LH(20)和Cramer SC(17);他们都是该领域积极且具有影响力的贡献者。图6A和B是由Citespace生成的包含831个节点及1 671条连线的作者共现图谱和聚类图。从图6B可见大部分作者主要研究方向集中在最佳治疗建议、中度缺血性损害、心肺适应性训练、质量评估、潜在获益方面。图5C显示了爆发性最强的12位作者,他们发表文章的数量在一定时间内迅速增加。爆发性强度排名前3的是:Yunhee Kim,Won Hyuk Chang与Yongil Shin。图5C可见Adam Kirton与Eric E Smith,Jacquie Hodge,Ephrem Zewdie,Bernadette T Gillick,Patrick Ciechanski及Helen L Carlson合作紧密。与Lee H Schwamm合作密切的作者有Eric E Smith,George Howard,Hakan Ay,Daiwai M Olson,Natalia S Rost,David J Lin, Janet Prvu Bettger及Gregg C Fonarow。 "
2.4 共被引分析 共被引分析是一种衡量不同文献、期刊或作者之间的关系程度的研究方法。3 098篇文献总共引用了96 736篇参考文献。表9列出了共被引次数最多的10篇参考文献。图6C,D分别显示了引用参考文献的共现和聚类。表10列出了前10个聚类标签。对缺血性脑卒中康复过去10年的聚类标签分析可见,引导式治疗机制、脑卒中存活、随机交叉、皮质脊髓束损伤、基于细胞治疗、共识核心推荐、运动功能恢复等是该领域的基础框架。表11,12列出了共被引次数及中心性最高的10个引用期刊,其中影响因子最高的3个期刊是《Lancet》(59.102)、《Lancet neurology》(28.755)及《Circulation》(23.054)。共被引次数和中心性排名前3的分别是《Stroke》(2 743),《Neurology》(1 429),《Archives of physical medicine and rehabilitation》(1 152)和《Journal of neuroscience》(1.11),《Journal of Cerebral Blood Flow and Metabolism》(0.81),《Neurology》(0.78)。这些顶级期刊上发表的文章反映了该研究领域的基础。 "
2.5 共词分析 关键词共现的视觉知识图谱反映了该领域的热点和前沿知识点。图4D为爆发性关键词,时间线图如图7所示,其中排除了关键词acute ischemic stroke,brain,brain ischemia,brain stimulation,cerebral ischemia,electroacupuncture,exercise,infarction,ischemia,stimulation,ischemic stroke,recovery,rehabilitation,transcranial magnetic stimulation,stroke rehabilitation,therapy及stroke。图6E是由310个节点和401条连线组成的该领域的关键词共词分析图谱。图6F的聚类图包含了18个聚类,其Q和S分别为0.789 6、0.920 2,18个聚类中有13个聚类的S > 0.9。最常与危险因素一起出现的词为人群、冠心病及预测者;与结果一起出现的关键词常为模型、护理、住院患者康复及髋部骨折;伴随生活质量出现的词是抑郁、健康;与偏瘫一起出现的是上肢、手功能、残疾和肌肉。引用次数最高的前100篇文献关键词聚类主要集中在卒中护理、重复经颅磁刺激、言语障碍、大脑动脉闭塞、海马神经元以及随机对照试验。此外,在一段时间内出现频次最高的爆发关键词为该领域的前沿知识点。图4D显示了爆发性最强的25个关键词,其中有意义的爆发词为大脑中动脉、花费、血管再生、一氧化氮合酶、功能磁共振成像等。从时间线视图来看,大部分关键词集中出现在2010至2014年。 "
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