Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (48): 7156-7162.doi: 10.3969/j.issn.2095-4344.2016.48.002
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Shi Li-jun, Bai Yu, Gao Fu-qiang, Sun Wei, Wang Wei-guo, Cheng Li-ming, Guo Wan-shou
Revised:
2016-08-28
Online:
2016-11-25
Published:
2016-11-25
Contact:
Sun Wei, Chief physician, Professor, Doctoral supervisor, Department of Orthopedics, China-Japan Friendship Hospital, Beijing 100029, China
About author:
Shi Li-jun, Studying for master’s degree, Department of Orthopedics, China-Japan Friendship Hospital, Beijing 100029, China
Bai Yu, Department of Orthopedics, China-Japan Friendship Hospital, Beijing 100029, China
Supported by:
the National Natural Science Foundation of China, No. 81273972; the Youth Science and Technology Talent Project of China-Japan Friendship Hospital, No. 2014-QNYC-A-06
CLC Number:
Shi Li-jun, Bai Yu, Gao Fu-qiang, Sun Wei, Wang Wei-guo, Cheng Li-ming, Guo Wan-shou . Cocktail therapy reduces hidden blood loss after total hip arthroplasty[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(48): 7156-7162.
2.1 参与者数量分析 对182例将要行首次全髋关节置换的患者进行筛选和评估,31例患者由于符合排除标准不能进入研究,23例患者拒绝参加试验。因此此次试验中,共128例患者参与了试验。将这些患者进行随机化分组后,有3例患者在术前退出,最终试验中共有125例患者,其中鸡尾酒组64例、氨甲环酸组61例。 2.2 基线资料比较 两组患者的人口学基线和临床特征无显著差别(P > 0.05),见表1,观察指标主要包括患者的性别、年龄、身高、体质量、体质量指数、Harris髋关节评分、ASA评分、血红蛋白浓度、红细胞比容和术前合并症,围手术期观察指标包括手术时间、皮肤切口长度住院日,这些指标测量由2名不参与此次试验的外科医师完成。"
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