Biomaterials in tooth regeneration: application and future

doi:10.3969/j.issn.2095-4344.2016.03.026

Abstract

Abstract:

BACKGROUND: The emergence of tissue engineering technology has provided a new possibility for the study of tooth regeneration. The biomaterials used in the research of tooth regeneration have a good implementation prospect, and have achieved some research results, which have become a study hotspot.
OBJECTIVE: To review the research history, types, characteristics of biomaterials and the research evelopments in the field of tooth regeneration.
METHODS: The articles about biomaterials and their applications in the tooth regeneration published during 2000 to 2015 were retrieved from CNKI, PubMed and Google Scholar by computer. Typical and creative research achievements were enrolled in result analysis.
RESULTS AND CONCLUSION: Many research results demonstrate that biomaterials play an irreplaceable role in tooth regeneration, among which the soft biomaterials can be used for wrapping cytoskeleton, whereas the mechanical rigid biomaterials act as the structural substitutes. Therefore, we can use these two kinds of biomaterials together and complementarily. Biomaterials and a variety of dental stem cells all have a good biocompatibility, low cytotoxicity and immunogenicity, which may induce some cells to differentiate toward a particular direction. As more and more research achievements of biomaterials in the field of tissue regeneration have been discovered, how to reduce the costs and realize the clinical applications still need further research.
中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Yu Yong, Deng Feng, Wu Yan . Biomaterials in tooth regeneration: application and future[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(3): 446-450.

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