Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (3): 441-445.doi: 10.3969/j.issn.2095-4344.2016.03.025

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The application of biodegradable absorbable materials in bone repair

Hou Li-gang, Yang Jian-yi   

  1. Second Department of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, Henan Province, China
  • Received:2015-11-26 Online:2016-01-15 Published:2016-01-15
  • About author:Hou Li-gang, Master, Attending physician, Second Department of Orthopedics, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, Henan Province, China

Abstract:

BACKGROUND: Because there are many inevitable problems in autologous or allogeneic bone grafting for treatment of bone defects, the application of biodegradable absorbable material is the focus of current research.
OBJECTIVE: To evaluate the biological properties of several kinds of bone repair materials and their influence on bone defect repair after implantation.
METHODS: PubMed and CNKI databases were retrieved for articles published from 1994 to 2015 by computer. The keywords were “bone defect, biodegradable material, bone graft” in English and Chinese, respectively. 
RESULTS AND CONCLUSION: Biodegradable absorbable materials mainly include natural polymer materials, synthetic polymer materials and bio-inorganic materials. Biodegradable absorbable materials have good biocompatibility, and can induce new bone ingrowth after implantation to form good osteo-integration. It has shown a clear advantage in bone repair. A variety of materials combined together can promote the repair of bone defects, which is the development trend of alternative materials for bone repair.