Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (3): 451-455.doi: 10.3969/j.issn.2095-4344.2016.03.027

Previous Articles    

Coronary stenting for myocardial infarction: its developmental trends

Miao Lei, Liu Pei-liang   

  1. Department of Cardiology, Liaoning Jinqiu Hospital, Shenyang 110016, Liaoning Province, China
  • Received:2015-11-07 Online:2016-01-15 Published:2016-01-15
  • Contact: Miao Lei, Department of Cardiology, Liaoning Jinqiu Hospital, Shenyang 110016, Liaoning Province, China
  • About author:Miao Lei, Master, Chief physician, Department of Cardiology, Liaoning Jinqiu Hospital, Shenyang 110016, Liaoning Province, China

Abstract:

BACKGROUND: Coronary stenting can effectively prevent the artery blood vessels against obstruction or stenosis due to fat accumulation and improve cardiac function in patients with myocardial infarction.
OBJECTIVE: To analyze the clinical trends of different types of coronary stents for myocardial infarction reported 
from 2004 to 2015 in Medline, CNKI, Wanfang, ClinicalTrials.gov and Chinese Clinical Trial Register.
METHODS: The relevant articles addressing metal bare stents, drug-eluting stents, and biodegradable stents were retrieved using the keywords of “stent” and “myocardial infarction” in Chinese and English in Medline, CNKI, Wanfang, ClinicalTrials.gov and Chinese Clinical Trial Register followed by statistical analysis. The retrieval time was from 2004 to 2015, including 2004-2007, 2008-2011 and 2012-2015.
RESULTS AND CONCLUSION: (1) In Medline database, there were 720 clinical studies about coronary stenting for myocardial infarction published from 2004 to 2015. The number of articles addressing drug-eluting stents continued to increase from 2004 to 2007, 2008 to 2011 and 2012 to 2015. The number of articles addressing metal bare stents reached the peak from 2008 to 2011, and then decreased. Biodegradable stents appeared after 2008, and the number of relevant articles was increased gradually. In CNKI and Wanfang databases, the number of metal bare stents for myocardial infarction was at a lower level, while the number of drug-eluting stents was peaked from 2008 to 2011, and at that time, biodegradable stents were rarely reported in China. (2) In ClinicalTrials.gov, the number of clinical trials about metal bare stents for myocardial infarction was relatively low, the number of clinical trials about drug-eluting stents was reduced dramatically from 2012 to 2015, but the number of clinical trials about biodegradable stents for myocardial infarction had a rising trend.