Balloon vertebroplasty repairs vertebral compression fractures: biomechanical analysis

doi:10.3969/j.issn.2095-4344.2015.53.016

Abstract

Abstract:

BACKGROUND: For vertebral compression fractures treated by balloon vertebroplasty, there were still controversies in biomechanical and clinical studies about adjacent vertebral fractures is the result of osteoporosis progress, or the result of vertebral intervention and strengthening by injecting bone cement. More accurate conclusions can be obtained through more in-depth research and long-term follow-up.
OBJECTIVE: To evaluate the effect of balloon vertebroplasty on biomechanical properties of vertebral body with compression fractures and unstrengthened adjacent vertebral body.
METHODS: Totally 40 pig specimens with vertebral compression fractures were prepared and randomly divided into study and control groups. Specimens in the study group were subjected to balloon vertebroplasty. Specimens in the control group only wrapped with normal saline gauze. The biomechanical properties (vertebral height, maximum load), stress, strain and displacement values of specimens under 500 N loading in these two groups were compared. The stress and strain values of unstrengthened adjacent vertebral body before and after the balloon vertebroplasty in the study group were measured, and compared with the control group.
RESULTS AND CONCLUSION: Compared with the original height, specimens in the study group can restore to its original height after balloon vertebroplasty, the differences were not significant (P > 0.05). The former, back, left and right vertebral height in the study group were significantly higher than those in the control group (P < 0.01). After the bone cement augmentation, the stiffness of vertebral body in the study group was significantly lower than that in the control group, the maximum loading was significantly increased compared with that in the control group (P < 0.05). Under a fixed loading of 500N, compared with the control group, the disc displacement value after the balloon vertebroplasty was significantly reduced and the disc strain and stress values were significantly increased in the study group (P < 0.05). There were no significant differences in the strain and stress values of the unstrengthened adjacent vertebral body before and after the balloon vertebroplasty in the study group (P > 0.05). There were no significant differences in the strain and stress values of the unstrengthened adjacent vertebral body after the balloon vertebroplasty between study group and control group (P > 0.05). These results suggest that vertebral maximum loading and stiffness recover well after the treatment of balloon vertebroplasty for vertebral compression fractures, which can achieve the effect of preventing vertebral fractures again. Meanwhile, balloon vertebroplasty treatment can not alter the biomechanical properties of adjacent vertebrae, and it is difficult to influence and lead vertebral fractures again, with a better security.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

CLC Number:

R318

Li Song-bai, Zhang Yuan-jin, Sun Fa-rui. Balloon vertebroplasty repairs vertebral compression fractures: biomechanical analysis[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(53): 8621-8626.

Figures/Tables 4

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