The clinical application of absorbable internal fixation system in maxillofacial fractures: systematic review and Meta-analysis

doi:10.3969/j.issn.2095-4344.2015.52.026

Abstract

Abstract:

BACKGROUND: There are numerous clinical studies on comparing absorbable internal fixation system and titanium metal internal fixation system in maxillofacial fractures; however, the systematic reviews and Meta-analysis in this field are rare.
OBJECTIVE: To compare the clinical effect of absorbable internal fixation system and titanium internal fixation system in maxillofacial fractures through systematic review and Meta-analysis.
MATERIALS AND METHODS: The randomized controlled trials and controlled clinical trials regarding the application of absorbable internal fixation system and titanium internal fixation system in maxillofacial fractures were electronically retrieved from Medline, Embase, the Cochrane Central Register of Controlled Trials, China Biology Medicine disc, and China Academic Journal Network Publishing Database using the keywords. Meta-analysis was conducted using Revman 5.3 software.
RESULTS AND CONCLUSION: Thirteen clinical studies were included, and totally 1 718 patients were involved. The Meta-analysis results showed that the removal rate of implants in the absorbable internal fixation system group was significantly lower than that in the titanium internal fixation group (P=0.000 2); there were no significant differences in the healing rate of fracture I stage, the incidence of insufficient fixation in fracture site and the incidence of long-term complications between these two groups. These results demonstrate that the efficiency and safety of absorbable internal fixation system in maxillofacial fracture is satisfactory, and can reduce the proportion of secondary surgical removal of the implant. More randomized controlled trials should be conducted to confirm this conclusion.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

CLC Number:

R318

Liu Hang-hang, Wu Chen-zhou, Pan Wei-yi, Su Zhi-fei, Duan Ze-xi, Shi Long, Li Chun-jie. The clinical application of absorbable internal fixation system in maxillofacial fractures: systematic review and Meta-analysis [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(52): 8509-8516.

Figures/Tables 6

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