Two kinds of artificial valve rings in the treatment of degenerative mitral regurgitation due to pure mitral valve ring expansion

doi:10.3969/j.issn.2095-4344.2015.16.022

Abstract

Abstract:

BACKGROUND: Incidence of degenerative mitral regurgitation show a gradual increase tendency, but there is no report on degenerative mitral regurgitation due to pure mitral valve ring expansion in China.
OBJECTIVE: To summarize the early and midterm outcomes of pure mitral valve annuloplasty in the treatment of degenerative mitral regurgitation due to pure mitral valve ring expansion.
METHODS: Forty-eight patients with degenerative mitral regurgitation due to pure mitral valve ring expansion underwent pure mitral valve annuloplasty, including 23 cases treated with Carpentier-Edwards Physio ring and 23 with SJMTM rigid saddle ring. After discharge, echocardiography was used to evaluate heart function and mitral regurgitation degree during the follow-up. The outcomes were compared between the two groups.
RESULTS AND CONCLUSION: There was no early death after operation and all cases were cured and discharged. All patients were followed up for 3 months to 4 years, and the cardiac function and mitral valve regurgitation were significantly improved (no mitral regurgitation in 36 cases, trivial mitral regurgitation in 10 cases and mild mitral regurgitation in 2 cases). According to NYHA grading, there were 32 cases of level I and 16 cases
of level II. The echocardiography showed that postoperative left atrium diameter, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, pulmonary artery systolic pressure and the ratio of regurgitation beam area to left atrial area were significantly lower than those before operation (P < 0.01). The left ventricular ejection fraction increased greatly (P < 0.01). There was no ring rupture, ring avulsion and hemolysis. Postoperative transvalvular pressure was less than 3 mm Hg. However, there were no significant differences in the above-mentioned parameters between the Carpentier-Edwards Physio ring and SJMTM rigid saddle ring groups. The results suggest that the pure mitral valve annuloplasty is excellent in the treatment of degenerative mitral regurgitation due to pure mitral valve ring expansion, through the right surgical techniques and the right choice of artificial valve ring.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: Heart Valves, Transplantation, Heart Valve Prosthesis Implantation

CLC Number:

R318

Han Jin-song1, Wang Hui-shan1, Yin Zong-tao1, Wang Ting-ting2, Han Hong-guang1, Song Heng-chang1, Jin Yan1, Zhu Yan1, Chen Zhao-hui1 . Two kinds of artificial valve rings in the treatment of degenerative mitral regurgitation due to pure mitral valve ring expansion[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(16): 2578-2582.

Figures/Tables 3

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