Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (18): 2908-2914.doi: 10.3969/j.issn.2095-4344.3833
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Deng Bo, Hong Hainan, Fan Yongyong, Cai Guoping, Feng Xingbing, Hong Zhenghua
Received:
2020-06-28
Revised:
2020-07-03
Accepted:
2020-08-07
Online:
2021-06-28
Published:
2021-01-12
Contact:
Hong Zhenghua, Chief physician, Department of Orthopedics, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
About author:
Deng Bo, Mater, Physician, Department of Orthopedics, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
CLC Number:
Deng Bo, Hong Hainan, Fan Yongyong, Cai Guoping, Feng Xingbing, Hong Zhenghua. Efficacy and safety of tourniquet application in total knee arthroplasty and only at the time of cementing: a meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2021, 25(18): 2908-2914.
2.3.2 失血量 4项研究报道了术中失血量[15,17-18,21],结果显示全程使用组少于安装假体时使用组[MD=-175.38,95%CI(-243.26,-107.50),P < 0.000 1],见图5A;5项研究报道了术后引流量[15,17-18,20-21],结果显示全程使用组多于安装假体时使用组[MD=65.71,95%CI(41.45,89.97),P < 0.000 1],见图5B;6项研究报道了总出血 量[11-13,17-18,21],结果显示两组总出血量比较差异无显著意义[MD=-141.48,95%CI(-363.49,80.52),P=0.21],见图5C;3项研究报道了隐性失血量[17-18,21],结果显示全程使用组多于安装假体时使用组[MD=141.44,95%CI(63.46,219.42),P=0.004],见图5D。 "
2.3.6 次要并发症发生率及下肢深静脉血栓 9项研究报道了次要并发症发生率[11-12,14-19,21]。9项研究的同质性较好(P=0.22,I2=25%),采用固定效应模型进行分析。结果显示,全程使用组的次要并发症发生率高于安装假体时使用组[RR=2.53,95%CI(1.42,4.52),P=0.002],见图9A。6项研究报道了下肢深静脉血栓[11-12,14,17,19,21]。6项研究的同质性较好(P=0.43,I2=0%),采用固定效应模型进行分析。结果显示,全程使用组的下肢深静脉血栓发生率高于安装假体时使用组[OR=2.68,95%CI(1.22,5.87),P=0.01],见图9B。 "
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