Percutaneous vertebroplasty in the treatment of vertebral hemangioma: bone cement operation

doi:10.3969/j.issn.2095-4344.2015.12.004

Abstract

Abstract:

BACKGROUND: Increasing studies have found that, percutaneous vertebroplasty and bone cement are characterized by few traumas, few bleeding, simple operation, rapid recovery, rapid pain relief, and effective efficacy. However, tumor recurrence, symptom improvement, bone cement leakage and other complications make people controversial.
OBJECTIVE: To explore and summarize clinical outcomes and safety of percutaneous vertebroplasty and bone cement for treating symptomatic vertebral hemangioma.
METHODS: Fifty-two cases patients of symptomatic vertebral hemangioma (including 21 male and 31 female, aged 16-63 years) were treated with percutaneous vertebroplasty and bone cement. The lesions were found at T₅-T₁₂ in 36 cases and at L₁-L₃ in 16 cases. Clinical outcomes such as Visual Analogue Scale, Oswestry Disability Index and modified Macnab criteria, as well as complication before and after surgery were evaluated.
RESULTS AND CONCLUSION: All 52 patients were followed up for at least 6 months after the operation. The Visual Analogue Scale and Oswestry Disability Index were significantly increased at 1 day, 3 weeks and 6 months post-surgery, when compared to before surgery (P < 0.05); the modified Macnab evaluation was excellent in 40 cases, good in 7 cases, fair in 3 cases, and poor in 2 cases, and the excellent and good rate was 90%. Only one patient had recurrence at 6 months after surgery and one patient had the leakage of bone cement. No other complications were found. Percutaneous vertebroplasty and bone cement could effectively cure vertebral hemangioma and relieve the pain, which is a safe treatment.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: Vertebroplasty, Hemangioma, Pain

CLC Number:

R318

Li Zu-guo, Tong Wei-hua, Liu Hao, Wu Ji-guang, Hu Zuo-hong. Percutaneous vertebroplasty in the treatment of vertebral hemangioma: bone cement operation[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(12): 1822-1826.

Figures/Tables 1

References

[1] Barzin M,Maleki I.Incidence of vertebral hemangioma on spinal magnetic resonance imaging in Northern Iran.Pak J Biol Sci.2009;12(6):542-544.
[2] Baudrez V,Galant C,Vande Berg BC.Benign vertebral hemangioma: MR-histological correlation.Skeletal Radiol. 2001;30(8):442-446.
[3] Terry Canale S.The tumor of spine.Campbell's Operative Orthopaedics,2008.11th edition.
[4] Robert G,Marek S,Max A.Vertebral tumors.Lippincott Williams &Wilkins,2008:83-84.
[5] Pastushyn AI,Slin'ko EI,Mirzoyeva GM.Vertebral hemangiomas: diagnosis, management, natural history and clinicopathological correlates in 86 patients.Surg Neurol.1998;50(6):535-547.
[6] Heyd R,Seegenschmiedt MH,Rades D,et al.Radiotherapy for symptomatic vertebral hemangiomas:results of a multicenter study and literature review. Int J Radiat Oncol Biol Phys. 2010; 77(1):217-225.
[7] Tanigawa N,Komemushi A,Kariya S,et al. Radiological follow-up of newcompression fractures following percutaneous vertebroplasty.Cardiovasc Intervent Radiol. 2006;29(1):92-96.
[8] Rodriguez-Catarino M.Percutaneous vertebroplasty-a new method for alleviation of back pain.Lakartidningen. 2002; 99(9):882-890.
[9] Muto M,Muto E,Izzo R,et al.Vertebroplasty in the treatment of back pain.Radiol Med.2005;109(3):208-219.
[10] Teng GJ,He SC,Deng G,et al.A simplified method of opacifying and mixing acrylic cement for percutaneous vertebroplasty: a clinical and in vitro study.Cardiovasc Intervent Radiol.2005;28(5):570-577.
[11] De Cosmo G,Aceto P,Gualtieri E,et al.Analgesia in Thoracic Surgery.Minerva Anestesiol.2009;75(6):393-400.
[12] Ruetten S,Komp M,Merk H,et al.Full-endoscopic interlaminar and transforaminal lumbar discectomy versus conventional microsurgical technique: a prospective,randomized,controlled study.Spine (Phila Pa 1976).2008;33(9):931-939.
[13] Maenab I.Negative disc exploration:ananalysis of the causes of nerveroot involvement in sixtyelght patients.J Bone Joint Surg Am.1971;53(5):891-893.
[14] Blecher R,Smorgick Y,Anekstein Y,et al.Management of symptomatic vertebral hemangioma: follow-up of 6 patients.J Spinal Disord Tech.2011;24(3):196-201.
[15] Pastushyn AI,Slin'ko EI,Mirzoyeva GM.Vertebral hemangiomas: diagnosis, management, natural history and clinicopathological correlates in 86 patients.Surg Neurol.1998;50(6):535-547.
[16] Fox MW,Onofrio BM.The natural history and management of symptomatic and asymptomatic vertebral hemangiomas.J Neurosurg.1993;78(1):36-45.
[17] Komemushi A,Tanigawa N,Kariya S,et al.Percutaneous vertebroplasty for osteoporotic compression fracture： multivariate study of predictors of new vertebral body fracture.Cardiovasc Intervent Radiol.2006;29(4):580-585.
[18] Aeosta FL Jr,Dowd CF,Chin C,et al.Curret treatment strategies and outeomes in the management of Sylllptomatic vertebral hemangiomas.Neurosurgery.2006;58(2):287-295.
[19] Bas T,Aparisi F,Bas JL.Efficacy and safety of ethanol injections in 18 cases ofvertebral hemangioma：a mean follow- up of 2 years.Spine (Phila Pa 1976).2001;26(14):1577-1581.
[20] Heyd R,Seegenschmiedt MH,Rades D,et al.Radiotherapy for symptomatic vertebral hemangiomas:results of a multicenter study and literature review.Int J Radiat Oncol Biol Phys.2010; 77(1):217-225.
[21] Singh P,Mishra NK,Dash HH,et al.Treatment of Vertebral Hemangiomas With Absolute Alcohol (Ethanol) Embolization, Cord Decompression, and Single Level Instrumentation:A Pilot Study.Neurosurgery.2011;68(1):78-84.
[22] Hrabálek L.Comprehensive therapy of symptomatic vertebral haemangiomas.Acta Chir Orthop Traumatol Cech.2010;77(2): 149-153.
[23] Galibert P,Deramond H,Rosat P,et al.Primary note on the treatment of vertebral angioma by Percutaneous acrylic vertebroplasty .Neurochirurgie.1987;33(2):166-168.
[24] Cohen JE,Lylyk P,Ceratto R,et al.Percutaneous vertebroplasty: technique and results in 192 procedures. Neurol Res.2004;26(1):41-49.
[25] Muto M,Muto E,Izzo R,et al.Vertebropalsty in the treatment of back pain.Radiol Med.2005;109(3):208-219.
[26] Weill A,Chiras J,Simon JM,et al.Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement.Radiology.1996;199(1):241-247.
[27] Reidy D,Ahn H,Mousavi P,et al.Abiomechanical analysis of intravertebral pressures during verteb roplasty of cadaveric spines with and without simul atedmetastases.Spine (Phila Pa 1976).2003;28(14):1534-1539.