Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (43): 8168-8170.doi: 10.3969/j.issn.2095-4344.2012.43.037

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Leukocyte reduction associated with Ni-Cr alloy porcelain crown: A case analysis

Fan Can-can, An Xiao-li, Che Xiao-qiang, Liu Bin   

  1. Stomatology School of Lanzhou University, Lanzhou 730000, Gansu Province, China
  • Received:2012-01-16 Revised:2012-03-26 Online:2012-10-21 Published:2012-10-21
  • Contact: Liu Bin, Doctor, Professor, Stomatology School of Lanzhou University, Lanzhou 730000, Gansu Province, China liubkq@lzu.edu.cn
  • About author:Fan Can-can, Stomatology School of Lanzhou University, Lanzhou 730000, Gansu Province, China Fancc07@lzu.edu.cn

Abstract:

BACKGROUND: It is known that Ni-Cr alloy porcelain crown can cause allergic reactions. Recently, their effects to whole body organs and functions also have attracted scholars' attention, especially for the influence on the kidney and immune system.
OBJECTIVE: To report and analyze a clinical suspected case of lower white blood cell count due to the Ni-Cr alloy porcelain crown, and to discuss the impact of Ni-Cr alloy porcelain crown on the immune system.
METHODS: According to the clinical special case, we inspected the general and oral conditions and removed the prosthesis which might cause diseases. Then we treated the related disease and restored the teeth with full porcelain crown. After a month, the patient came back for review and we compared the results of hemogram before and after treatment. Referring to literatures, we also analyzed the possibility of white blood cell count reduction caused by Ni-Cr alloy porcelain crown.
RESULTS AND CONCLUSION: The change of white blood cell count after the removal of Ni-Cr alloy porcelain crown and all-ceramic crowns restoration could verify the conjecture that the Ni-Cr alloy porcelain crown caused the reduction of white blood cell count. The data also showed that the Ni-Cr alloy porcelain crown could influence the immune function through certain ways, which should arouse the attention of dental doctors. Therefore we should take certain measures to avoid these negative effects.

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