Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (43): 8163-8167.doi: 10.3969/j.issn.2095-4344.2012.43.036

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Diagnostic value of dual-source CT coronary angiography in detecting coronary-stent restenosis

Hu Gang-feng1, Bao Jian1, Qian Ping-yan1, Qian Bin1, Hu Xiao-hua2, Wu Jing-tao2   

  1. 1Department of Radiology, Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, Jiangsu Province, China
    2Department of Radiology, Clinical Medical College of Yangzhou University, Yangzhou 225001, Jiangsu Province, China
  • Received:2012-03-15 Revised:2012-05-28 Online:2012-10-21 Published:2012-10-21
  • About author:Hu Gang-feng, Technician in-charge, Department of Radiology, Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, Jiangsu Province, China 1067019959@qq.com

Abstract:

BACKGROUND: The traditional CT is hard to be popularized in follow-up after the treatment of coronary heart disease with interventional stents, looking for noninvasive and effective method to evaluate the stent restenosis has became the hot spot.
OBJECTIVE: To investigate the diagnosis value of dual-source CT coronary angiography in detecting coronary-stent restenosis through the comparing the evaluative effect of dual-source CT coronary angiography and selective coronary angiography without heart rate control.
METHODS: The 53 cases with a total of 75 stents were performed with dual-source CT coronary angiography and coronary angiography to evaluate image quality and analyze sensitivity of coronary-stent restenosis.
RESULTS AND CONCLUSION: ①All stents were considered assessable for diagnosis with dual-source CT angiography. Images quality of 96% (72/75) of the stents was good. ②There was no significant difference in sensitivity, specificity, positive and negative predictive value and the accuracy between dual-source CT angiography diagnose in-stent restenosis and coronary angiography diagnose in-stent restenosis (P > 0.05). ③There was no significant difference in sensitivity, specificity, positive and negative predictive value and the accuracy between the patients with the heart rate < 70 beats/min and ≥ 70 beats/min receiving dual-source CT angiography diagnosis for in-stent restenosis (P > 0.05). ④The dual-source CT angiography had lower sensitivity, specificity, positive and negative predictive value and accuracy to detect < 3.0 mm in-stent restenosis than to detect ≥ 3.0 mm in-stent restenosis (P < 0.05). The dual-source CT is helpful for the evaluation of coronary in-stent restenosis without heart rate control, and it can be used as the large-diameter stent patency assessment method and small-diameter stent preliminary screening method.

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