Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (43): 8159-8162.doi: 10.3969/j.issn.2095-4344.2012.43.035

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Clinical comparison of reimplanted metallic and plastic biliary stents for occluded primary metallic stents in malignant biliary obstruction

Zhang Nuo-bei, Huang Nian-gen   

  1. Department of Digestion, the Second Hospital Affiliated to Nanchang University, Nanchang 330006, Jiangxi Province, China
  • Received:2012-02-08 Revised:2012-03-24 Online:2012-10-21 Published:2012-10-21
  • About author:Zhang Nuo-bei★. Master, Department of Digestion, the Second Hospital Affiliated to Nanchang University, Nanchang 330006, Jiangxi Province, China znbcx@ yahoo.com.cn

Abstract:

BACKGROUND: Reimplantation of metallic and plastic biliary stents in the obstructed scents can solve obstruction. However, it is debatable what a kind of combinations in stents can have more benefits for patients.
OBJECTIVE: To compare clinical effects of the reimplanted different kinds of stents for occluded primary metallic stents in malignant biliary obstruction.
METHODS: Totally 83 patients with malignant biliary obstruction were collected. They underwent endoscopic metal biliary endoprothesis and secondary biliary stent placement in the medium and low levels of the other stent as “stent-in-stent” in the Second Affiliated Hospital of Nanchang University. The patients were divided into three groups according various combinations in primary and secondary implanted stents: covered metallic stent group, uncovered metallic stent group and plastic stent group (5 covered-plastic, 10 uncovered-plastic).
RESULTS AND CONCLUSION: After the primary metallic stent was obstructed, the patent time of reimplanted covered metallic stents was significantly longer than that of plastic stents (P < 0.05). Compared with the uncovered metallic stent group, the cumulative patent time in the covered metallic stent group was obviously longer (P < 0.05-0.01). These results suggest that as the primary metallic stents were obstructed, covered metallic stents (at least one in the primary and/or secondary procedure) can provide longer cumulative patent time than uncovered metallic stents in both procedures for malignant biliary obstruction at medium and low levels treated by mendoscopic metal biliary endoprothesis.

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