Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (15): 2370-2374.doi: 10.3969/j.issn.2095-4344.3805

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Effect of lumbopelvic sagittal parameters on secondary adjacent vertebral fracture after percutaneous kyphoplasty for osteoporotic vertebral compression fracture

Zhang Le, Pan Bin, Ruan Ruxin, Guo Kaijin   

  1. Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China
  • Received:2020-06-20 Revised:2020-06-23 Accepted:2020-07-09 Online:2021-05-28 Published:2021-01-05
  • Contact: Guo Kaijin, Professor, MD, Chief physician, Master's supervisor, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China
  • About author:Zhang Le, Master candidate, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China
  • Supported by:
    National Natural Science Foundation of China, No. 81801213 (to PB); the Scientific Research Project of Jiangsu Provincial Health and Family Planning Commission, No. H201528 (to GKJ); the Key Social Development Project of Jiangsu Provincial Science and Technology Department, No. BE2015627 (to GKJ)

Abstract: BACKGROUND: In recent years, some scholars consider that the secondary adjacent vertebral fracture after percutaneous kyphoplasty may be related to the sagittal imbalance caused by changes in lumbopelvic alignment.   
OBJECTIVE: To explore the effect of lumbopelvic sagittal parameters on secondary adjacent vertebral fracture after percutaneous kyphoplasty in patients with lumbar osteoporotic vertebral compression fracture. 
METHODS: The clinical data of 67 patients with single segmental lumbar osteoporotic vertebral compression fractures who had undergone percutaneous kyphoplasty from January 2017 to January 2019 at the Affiliated Hospital of Xuzhou Medical University were recruited for retrospectively analysis. Of them, 32 patients suffered from secondary adjacent vertebral fracture, and 35 patients did not suffer from secondary vertebral fracture. The lumbar lordosis, pelvic incidence, pelvic tilt, sacral slope, sacrum pubic incidence and sacrum pubic posterior angle were compared between the secondary group and non-secondarygroup according to the postoperative lumbar posteroanterior and lateral radiographs, and the correlation between lumbar parameter and pelvic parameter in the secondary group was also analyzed. The study was approved by Ethics Committee of the Affiliated Hospital of Xuzhou Medical University. 
RESULTS AND CONCLUSION: (1) Both groups were followed up for more than 1 year. (2) The lumbar lordosis, pelvic incidence, sacral slope, sacrum pubic incidence and sacrum pubic posterior angle in the secondary group were less than those in the non-secondary group (P < 0.05). There was no significant difference in pelvic tilt between the two groups (P > 0.05). (3) Pearson correlation analysis showed that lumbar lordosis was correlated with pelvic incidence, sacrum pubic incidence and sacrum pubic posterior angle (P < 0.01), but was not related to pelvic tilt and sacral slope (P > 0.05). (4) The results showed that smaller lumbar lordosis and sacral slope can increase the risk of secondary adjacent vertebral fracture after percutaneous kyphoplasty in patients with single segmental lumbar osteoporotic vertebral compression fractures. The larger pelvic incidence, sacrum pubic incidence, and sacrum pubic posterior angle are protective factors against secondary adjacent vertebral fracture after percutaneous kyphoplasty in patients with single segmental lumbar osteoporotic vertebral compression fractures. 

Key words: bone, fracture, osteoporosis, sagittal parameters, percutaneous kyphoplasty, adjacent vertebral fracture

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