Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (39): 5852-5858.doi: 10.3969/j.issn.2095-4344.2016.39.012

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Application of a three-dimensional printing model of surgical decompression for cervical ossification of the posterior longitudinal ligament

Yuan Feng, Lu Hai-tao, Deng Bin, Li Zhi-duo, Li Wei, Wu Ji-bin, Guo Kai-jin   

  1. Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China
  • Revised:2016-08-15 Online:2016-09-23 Published:2016-09-23
  • Contact: Yuan Feng, M.D., Chief physician, Professor, Master’s supervisor, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China
  • About author:Yuan Feng, M.D., Chief physician, Professor, Master’s supervisor, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China
  • Supported by:

    the Six Peak Talents Foundation of Jiangsu Province

Abstract:

BACKGROUND: Three-dimensional (3D) printing technology has been successfully used in the field of joint replacement, fracture fixation and spinal implant, but the potential of 3D printing technology in the field of surgery for ossification of posterior longitudinal ligament of cervical spine remains to be discussed. OBJECTIVE: To determine the application value of a 3D printing model in the selection of anterior and posterior surgical decompression for cervical ossification of the posterior longitudinal ligament.

METHODS: A retrospective analysis was carried out involving 15 patients with ossification of the posterior longitudinal ligament collected by computed tomography (CT) and printed by a 3D model pre-operatively between October 2014 and October 2015 in Affiliated Hospital of Xuzhou Medical University. There were isolated type (n=2), segmental type (n=6), continuous type (n=4), and combined type (n=3). The application value of a 3D printer model in patients with ossification of the posterior longitudinal ligament was evaluated by Japanese Orthopedic Association scores, Visual Analog Scale scores, symptoms, and imaging data 1 month pre-operatively, 1 month post-operatively, and at the final follow-up.
RESULTS AND CONCLUSION: (1) All 15 patients underwent successful treatment of cervical spine decompression surgery and were followed up for 4-16 months. The post-operative symptoms were relieved more significantly than the pre-operative symptoms. Using the posterior approach for cervical spinal surgery, 1 patient had incision fat necrosis and healed after negative pressure drainage. (2) Japanese Orthopedic Association scores 1 month pre-operatively, 1 month post-operatively, and at the final follow-up were 9.0±1.6, 11.7±1.8, and 15.5±1.4, respectively; the differences were statistically significant (P < 0.05). Visual Analog Scale scores 1 month pre-operatively, 1 month post-operatively, and at the final follow-up were 6.7±2.5, 2.13±1.4, and 1.4±0.5, respectively; the difference was statistically significant (P < 0.05). (3) The imaging results at follow-up showed that the anterior interbodies were fused, and the pivot of the posterior operation was healed well without a re-closing phenomenon. (4) A 3D printer model was shown to be beneficial in observing the characteristics of cervical ossification of the posterior longitudinal ligament, performing the pre-operative evaluation, and simulating the surgical procedure. There was value for the choice of operative approach. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Cervical Vertebrae, Pain Measurement, Ossification of Posterior Longitudinal Ligament, Tissue Engineering

CLC Number: