Adjacent segment degeneration after anterior cervical corpectomy and fusion

doi:10.3969/j.issn.2095-4344.2016.35.007

Abstract

Abstract:

BACKGROUND: In recent years, the researchers have studied the adjacent segment degeneration after cervical fusion. Several studies concerned the adjacent segment degeneration after anterior cervical corpectomy and fusion.

OBJECTIVE: To evaluate the correlative factors of adjacent segment degeneration after anterior cervical corpectomy and fusion.

METHODS: 122 patients were included in the study from 126 patients who underwent anterior cervical corpectomy and fusion that operated by the same treatment team and involved a single vertebral body and the two plates between February 2009 and February 2012. The final follow-up period was 3 years. According to the degeneration progress of adjacent segment degeneration, these patients were divided into non-progression group and progression group. The gender, age, preoperative adjacent segment degeneration, cervical range of motion, upper and lower vertebral range of motion, surgical segment, titanium mesh subsidence, plate-to-disc distance, and cervical curvature index were compared between two groups. Logistic regression analysis was applied to analyze the correlative factors of adjacent segment degeneration.

RESULTS AND CONCLUSION: (1) There were significant differences in preoperative adjacent segment degeneration, postoperative cervical range of motion, postoperative upper and lower vertebral range of motion, and postoperative cervical curvature index (P < 0.05), which were included in logistic regression analysis. (2) Logistic regression analysis regression model: adjacent segment degeneration=0.317× postoperative cervical range of motion+3.374×preoperative adjacent segment degeneration+1.862 × postoperative lower vertebral range of motion-0.795×postoperative cervical curvature index-16.481. Logistic regression analysis demonstrated that preoperative range of motion, postoperative cervical range of motion, postoperative lower vertebral range of motion and postoperative cervical curvature index were correlative factors of range of motion after adjacent segment degeneration (P < 0.05). (3) These results indicated that preoperative adjacent segment degeneration, postoperative cervical range of motion, postoperative lower vertebral range of motion and postoperative cervical curvature index were correlative factors of adjacent segment degeneration. We should actively carry out effective measures to prevent the progress of the adjacent segment degeneration before, during and after anterior cervical corpectomy and fusion.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cervical Vertebrae, Spinal Fusion, Follow-Up Studies, Tissue Engineering

CLC Number:

R318

Zhai Peng-fei, Liu Wei, Sun Zhi-ming, Zhang Xue-li. Adjacent segment degeneration after anterior cervical corpectomy and fusion[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(35): 5216-5223.

Figures/Tables 5

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