Biocompatibility of Sextant minimally invasive pedicle screw fixation for osteoporotic vertebral fractures in the elderly

doi:10.3969/j.issn.2095-4344.2016.31.006

Abstract

Abstract:

BACKGROUND: Pedicle screw internal fixation is a commonly used method to treat osteoporotic fracture. Internal fixation can effectively reconstruct vertebral body height, restore physiological curvature, and maintain good spinal stability.

OBJECTIVE: To investigate the biocompatibility of minimally invasive percutaneous pedicle screw (Sextant) fixation in the treatment of elderly patients with osteoporotic vertebral fractures.

METHODS: A total of 71 cases of senile osteoporotic vertebral fractures were given minimally invasive percutaneous pedicle screw (Sextant) fixation for treatment. The C-arm X-ray machine was used to accurately locate the fracture vertebral body in different patients, and the corresponding surface was marked. In order to separate the subcutaneous tissue and fascia layer, the internal fixation with Sextant screw was used. 12 months after operation, the fixator was removed. The patients were followed up for 12 months, complications and tissues surrounding the fixator were observed. At 1, 3, 6, and 12 months after treatment, changes in Cobb angle, visual analogue scale score and Oswestry disability index were observed.

RESULTS AND CONCLUSION: (1) The average operation time was 90.25 minutes; intraoperative blood loss was 85.15 mL. (2) At different time points after treatment, Cobb angle, visual analogue scale score and Oswestry disability index of the patients were significantly decreased at 1 month after treatment, and maintained stable from then on. Cobb angle, visual analogue scale score and Oswestry disability index were significantly less at 1, 3, 6 and 12 months after treatment compared with that before treatment (P < 0.05). There was no significant difference in each indicator at different time points after treatment (P > 0.05). (3) Two patients affected wound infection, and were cured after symptomatic treatment. No complications such as thrombosis appeared. During removal of the screw, surrounding tissues were observed. There was no inflammatory hyperplasia of soft tissue around the fixator. No fibrous tissue or black wall was found. (4) These results confirm that Sextant minimally invasive pedicle screw internal fixation in elderly patients with osteoporotic vertebral fractures can obtain satisfactory therapeutic effect, and has good biocompatibility.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Spinal Fractures, Osteoporosis, Internal Fixators, Tissue Engineering

CLC Number:

R318

Wu Jian-jun. Biocompatibility of Sextant minimally invasive pedicle screw fixation for osteoporotic vertebral fractures in the elderly[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(31): 4603-1609.

Figures/Tables 3

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