Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (26): 3929-3937.doi: 10.3969/j.issn.2095-4344.2016.26.020

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Meta-analysis of death risk factors for hip fracture in the elderly

Wang Xin   

  1. Department of Orthopedics, Tianjin Port Hospital, Tianjin 300456, China
  • Revised:2016-04-12 Online:2016-06-24 Published:2016-06-24
  • About author:Wang Xin, Attending physician, Department of Orthopedics, Tianjin Port Hospital, Tianjin 300456, China

Abstract:

BACKGROUND: At present, with the aging trend of the world’s population and social development, the proportion of hip fracture is on the rise, and the morbidity and mortality rate are high. Therefore, it is necessary to analyze the risk factors for death in old patients with hip fractures. 

OBJECTIVE: To review and systematically analyze the death risk factors for hip fracture all over the world.
METHODS: The PubMed, Medline, EMBASE, the Cochrane library, China Knowledge Resource Integrated Database, VIP database resources were reviewed for mortality risk factors for hip fracture in the elderly. Meta analysis of mortality risk factors for hip fracture in the elderly was conducted by Stata11.0 software, and then the pooled odd ratio (ORs) and 95% confidence interval (95% CI) of each risk factor were calculated from the patient’s own factors and iatrogenic factors in order to analyze risk factors for hip fracture in the elderly.
RESULTS AND CONCLUSION: (1) 47 literatures were searched and among them 27 literatures were included in our meta-analysis. (2) The results of meta-analysis showed that mortality risk factors for hip fracture in the elderly included male, older than 60 years of age, body mass index, high American Society of Anesthesiologists Score, delay time from fracture to surgery, poor daily living before fracture, type of fracture, pre-fracture lung disease, pre-fracture cardiovascular disease, and pre-fracture dementia. (3) Results indicated that high mortality of the elderly patients with hip fractures possibly resulted from combined actions of physiological condition, operative factors and postoperative rehabilitation. Before treatment, fully understanding the patient’s physical function and health status, fully assessing the risk of surgery, and selecting the appropriate type of surgery can reduce complication rate and mortality and improve patients’ prognosis. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Hip Fractures, Aged, Risk Factors, Death, Meta-Analysis, Tissue Engineering

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