Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (16): 2557-2561.doi: 10.3969/j.issn.2095-4344.2015.16.018

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Long-term effects of five kinds of pulp capping agents: a comparative study

Nie Er-min, Jiang Rui, Zhang Chun-yuan, Zeng Jin-di, Tan Ji-zhou   

  1. Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • Received:2015-02-10 Online:2015-04-16 Published:2015-04-16
  • Contact: Zhang Chun-yuan, Master, Professor, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • About author:Nie Er-min, Master, Attending physician, Department of Stomatology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • Supported by:

    the Social Development Project of Guangdong Provincial Science and Technology Department, No. 2011B080701010, 2012B061700066

Abstract:

BACKGROUND: In the deep caries treatment, the pulp capping agent used in indirect pulp can induce the formation of dentin bridge (the complex of dental pulp and dentin), to protect the pulp tissue from stimulus and save the pulp vitality, completely avoid the occurrence of complications, with a higher clinical success rate.
OBJECTIVE: To evaluate the differences in clinical efficacy of five kinds of calcium hydroxide preparations.
METHODS: Totally 236 patients with deep caries were selected and randomized to undergo indirect pulp with the double-component calcium hydroxide powder (n=46), Metapex with one-component injection dosage form and the chemical curing calcium hydroxide preparation (n=47), Dycal with the chemical curing calcium hydroxide preparation (n=45), Ionosit-Baseliner (n=49) and Calcimol LC (n=49) with one-component and the light curing calcium hydroxide preparation. The status of the dental pulp, the restoration and the root tip were observed at 1, 6, 12 and 24 months after operation.
RESULTS AND CONCLUSION: There was no significant difference between the five groups in the success rate of indirect pulp capping at 1, 6 and 12 months (P > 0.05). At 24 months, the success rate of indirect pulp capping in the double-component calcium hydroxide powder group was lower than that in the other four groups (P < 0.05), but there was no significant difference between the latter four groups (P > 0.05). Metapex, Dycal, Ionosit-Baseliner and Calcimol LC all have a good effect on indirect pulp capping to deep caries, which can be used as agents for long-term pulp protection.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


全文链接:

Key words: Dental Pulp Capping, Pulp Capping and Pulpectomy Agents, Dental Caries

CLC Number: