Main cariogenic microorganisms: a Meta-analysis

doi:10.3969/j.issn.2095-4344.2015.34.028

Abstract

Abstract:

BACKGROUND: Scholars have carried out a lot of research on the main cariogenic microorganisms, but there is still no comprehensive and systematic evaluation.

OBJECTIVE: To perform an evidence-based medicine analysis on the six main cariogenic microorganisms.

METHODS: Literature about microbial factors and age factors of caries disease etiology were retrieved, which were published from 2011 to 2014 in the Cochrane Library, EMBASE, PubMed, Wanfang, China Biology Medicine disc (CBMdisc), Chinese Journal Full-text Database (CJFD) and VIP. Eligible studies were divided into two groups according to absorbance values: observation group (higher absorbance value) and control group (lower absorbance value). The probability of dental caries under the impact of Streptococcus mutans, Lactobacillus microbe, Prevotella, Selenomonas, Capnocytophaga, Veillonella were statistically analyzed using Meta-analysis.

RESULTS AND CONCLUSION: Eight articles were included in result analysis. Odds ratio (OR) values refer to the statistical difference in the probability of dental caries under same pathogenic factors between two groups: OR > 1 indicates the incidence of dental caries is higher in the observation group than the control group, and OR < 1 suggests the incidence of dental caries is lower in the observation group than the control group. Meta-analysis results show Streptococcus mutans (OR=2.41), Lactobacillus microbe (OR=1.68), Prevotella (OR=2.75),
Capnocytophaga (OR=1.98), Selenomonas (OR=2.38), indicating that the probability of dental caries is higher in the observation group than the control group, and these microorganisms are greatly correlated with the occurrence and development of dental caries; Veillonella (OR=0.45), indicating the probability of dental caries is lower in the observation group than the control group, and Veillonella has small correlation with dental caries and only plays an important role in a certain development stage of dental caries.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Dental Caries Susceptibility, Streptococcus, Meta-Analysis

CLC Number:

R318

Ye Yi-liao, Jia Yu-huan, Huang Wen-ming, Zheng Yu-qi. Main cariogenic microorganisms: a Meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(34): 5559-5566.

Figures/Tables 5

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