Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (48): 7769-7774.doi: 10.3969/j.issn.2095-4344.2014.48.011
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Wang Shi-jun1, Li Yu-ting2, Li Chun-de1, Liu Xian-yi1, Sun Hao-lin1, Wang Tian-long2
Received:
2014-10-23
Online:
2014-11-26
Published:
2014-11-26
Contact:
Li Chun-de, Doctoral supervisor, Chief physician, Department of Orthopedics, Peking University First Hospital, Beijing 100034, China
About author:
Wang Shi-jun, M.D., Attending physician, Department of Orthopedics, Peking University First Hospital, Beijing 100034, China
CLC Number:
Wang Shi-jun, Li Yu-ting, Li Chun-de, Liu Xian-yi, Sun Hao-lin, Wang Tian-long. Analgesic effect of ropivacaine complex liquid injection around the wound in lumbar fusion surgery[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(48): 7769-7774.
2.1 参与者数量分析 按意向性处理,纳入腰椎管狭窄症患者90例,按随机数字表法分为两组:试验组45例,对照组45例。全部进入结果分析,无脱落。 2.2 基线资料比较 共纳入90例患者,两组患者的年龄、男女比例、身高、体质量、体质量指数、手术时间及融合前目测类比评分等资料比较差异均无显著性意义,具有可比性 (表1)。 2.3 术后目测类比评分 试验组和对照组融合后目测类比评分均在融合后2 h最高,之后随着时间推移逐渐减少。试验组在融合后2,4,8,12,24 h的目测类比评分均低于对照组,两组间差异有显著性意义(P < 0.05,表2)。 2.4 术后芬太尼使用量及药物不良反应情况 试验组的静脉自控镇痛泵按压次数低于对照组,两组间差异有显著性意义(P < 0.001)。 试验组的融合后芬太尼使用总量低于对照组,两组间差异有显著性意义(P < 0.001)。试验组的恶心、呕吐发生率低于对照组,但差异无显著性意义(P > 0.05),见表3。 两组间均未出现心律失常、低血压及过敏反应。"
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