Efficacy of neuromuscular electrical stimulation on pain of patients with knee osteoarthritis: a meta-analysis

doi:10.3969/j.issn.2095-4344.2014.38.028

Abstract

Abstract:

BACKGROUND: Symptomatic treatment is the main management strategy for patients with knee osteoarthritis at early metaphase. Some previous studies have demonstrated that neuromuscular electrical stimulation can alleviate pain in knee osteoarthritis patients. To date, this effectiveness, however, still remains controversial.
OBJECTIVE: To assess the efficacy of neuromuscular electrical stimulation on pain in patients with knee osteoarthritis.
METHODS: Randomized controlled trials concerning the efficacy of neuromuscular electrical stimulation in the treatment of knee osteoarthritis were identified from the Medline database conducted up to July 3, 2014. These studies were selected independently by two reviewers according to the inclusion and exclusion criteria. Meta-analysis was performed using Revman5.2 software.
RESULTS AND CONCLUSION: A total of 5 randomized controlled trials consisting of 239 participants were included. The results of the meta-analysis indicate neuromuscular electrical stimulation has no significant impact on measure of pain in knee osteoarthritis patients in comparison to the blank control group [mean difference= -0.40, 95% confidence interval (-1.34-0.54), P=0.40]. Owing to the sample limitations of our study, it is hard for us to draw a conclusion that the application of neuromuscular electrical stimulation in managing pain in patients with knee osteoarthritis is of little significance. Further work based on large-sample and high-quality
randomized controlled trials is needed to determine the role of neuromuscular electrical stimulation in pain in this population.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

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Key words: osteoarthritis, knee joint, pain, transcutaneous electric nerve stimulation

CLC Number:

R318

Xie Dong-xing, Wang Yi-lun, Li Hui, Yang Tuo, Deng Zhen-han, Yang Ye, Zhang Yi, Ding Xiang,Lei Guang-hua. Efficacy of neuromuscular electrical stimulation on pain of patients with knee osteoarthritis: a meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(38): 6228-6232.

Figures/Tables 3

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