Effect of stratified vessels on fluid-solid interaction of heart valves

doi:10.3969/j.issn.2095-4344.1418

Abstract

Abstract:

BACKGROUND: The main treatment for valvular heart disease is heart valve replacement. The design and performance optimization of artificial heart valves are currently the areas of research. Numerical analysis and experimental methods are major keys to analyzing the mechanical properties of artificial heart valves. Analyzing the mechanical properties of the valves by finite element method and displaying the mciro-stress of the valves in vivo provide more accurate data for the design and performance optimization of artificial heart valve.

OBJECTIVE: To establish a more realistic vascular model and investigate the effects of stratified vessels on the deformation characteristics and stress distribution of aortic valves, providing theoretical mechanical data for further improving the design of artificial heart valve.

METHODS: Finite element geometric models and mathematical models including aortic valve, vessel wall and blood were established, in which the vessel wall was stratified. The effects of stratification characteristics on the fluid-solid interaction deformation and stress of the aortic valve were investigated to verify the importance of the stratified vessel wall.

RESULTS AND CONCLUSION: Valve deformation mainly occurred in the leaflets, the arterial wall had no obvious deformation, the highest level of free deformation was observed at the leaflet free edge. The deformation from the free edge of the leaflet to the suture edge showed a gradient decrease tendency. The maximum equivalent stress of the whole heart valve model was located on the outer arterial wall (near the suture point of the valve leaflet and the arterial wall). The inner and outer arterial walls were greatly different in force. The equivalent stress value of the inner arterial wall was much smaller than that of the outer arterial wall. The stress between inner and outer arterial walls was not continuous. The maximum equivalent stress of the leaflets was at the suture edge of the leaflets and the arterial wall. Compared with the previous studies that did not consider the stratification characteristics of the arterial wall, the maximum equivalent stress value of the leaflets was closer to the ex vivo failure stress of the human mitral valve leaflets.

Key words: valvular heart disease, artificial heart valve, stratified vessel, fluid-solid interaction, data analysis, mechanical performance, deformation analysis, stress analysis

CLC Number:

Liu Xingming, Yuan Quan, Cong Hua, Zhu Hongwei. Effect of stratified vessels on fluid-solid interaction of heart valves[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(30): 4799-4803.

Figures/Tables 5

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