Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (30): 5665-5668.doi: 10.3969/j.issn.1673-8225.2011.30.038

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Bone defect repair in the surgical treatment of spinal tuberculosis

Yang Zhi-xian, Peng Xiao-zhong, Wu Zhen-guo, Wei Han-yu, Lei Cheng-gang, Huang Zhan-zhu   

  1. Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou  545005, Guangxi Zhuang Autonomous Region, China
  • Received:2011-03-05 Revised:2011-06-20 Online:2011-07-23 Published:2011-07-23
  • Contact: Peng Xiao-zhong, Associate chief physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China pxz@163.com
  • About author:Yang Zhi-xian, Associate chief physician, Department of Spinal Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China yangzhixiann@163.com

Abstract:

BACKGROUND: How to repair damage to the vertebral body using surgical methods is important and difficult for treatment of spinal tuberculosis
OBJECTIVE: To learn a variety of the methods to repair bone defects in spinal tuberculosis after lesions removal in China at present, and to find out the effective methods and new progress.
METHODS: CNKI database was search for  the literature related to surgical treatment of spinal tuberculosis published 2006/2010-01-01. First, the key word of “spinal tuberculosis” was used and then “internal fixation”, “bone graft”, “synthetic bone (materials)”, “titanium mesh”, “bone cement”, “artificial vertebral body” were used as key words in the above data retrieval. According to selected conditions, the relevant literature with reported cases, surgical procedures (including bone repair method), effects (including cure rate, relapse rate, Cobb angle corrected) were selected for statistical analysis.
RESULTS AND CONCLUSION: Autologous bone (iliac, ribs) is the major source of repaired bone defects in spinal tuberculosis, followed by titanium mesh and bone graft, and a small amount of synthetic bone and artificial vertebral body is used for clinical treatment. In the future, synthetic bone and the artificial vertebral body have a broad development space, being an ideal substitute.

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