Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (30): 5535-5538.doi: 10.3969/j.issn.1673-8225.2011.30.007

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Automatic location and extraction method for phalangeal epiphyseal range of interest 

Ran Long-ke1, 2, Song Fang-zhou3, 4, Tan Peng-cheng1, Jin Jing1   

  1. 1Department of Computer, School of Basic Medicine, 2Laboratory of Forensic and Biology Information Technology, 3Department of Biochemistry and Molecular Biology, 4Center of Molecular Medicine and Oncology, Chongqing Medical University, Chongqing  400016, China
  • Received:2011-05-18 Revised:2011-06-20 Online:2011-07-23 Published:2011-07-23
  • Contact: Song Fang-zhou, Doctor, Professor, 1Department of Biochemistry and Molecular Biology, 2Center of Molecular Medicine and Oncology, Chongqing Medical University, Chongqing 400016, China
  • About author:Ran Long-ke★, Master, Lecturer, 1Department of Computer, School of Basic Medicine, 2Laboratory of Forensic and Biology Information Technology, Chongqing Medical University, Chongqing 400016, China ranlk@sina.com
  • Supported by:

    Science and Technology Projects of Yuzhong District, Chongqing City*

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Abstract:

BACKGROUND: At present, several methods are dissatisfactory for extracting epiphyseal/metaphyseal region of interest (EMROIs), which leads to poor reorganization effects and assessment accuracy of bone age.
OBJECTIVE: To overcome the difficulties of EMROI extraction and extraction method limitations based on k-cosine algorithm to local key points of the phalanx.
METHODS: EMROI were extracted and filtered by anisotropic anisotropic diffusion. The statistics of phalanx images data were analyzed and found out the method for locating the central points of the phalanx. A third-order polynomial was used to fit the central axis line according to the central points, and epiphyseal ROIs were then extracted.
RESULTS AND CONCLUSION: Great deals of experiments are showed that the central axis line located by this method is correct, which reflects the real skeleton of the phalanx. On this basis, EMROI can be extracted, and the success rate rises to 95%. And the method can be applied to evaluate EMROI in the following research.

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