Abstract:

BACKGROUND: Drug-eluting stent significantly reduced the restenosis of stent implantation in the coronary artery, and its application became extensive.
OBJECTIVE: To investigate how to elevate the compatibility of drug-eluting stent in elderly cardiovascular disease from aspects of material and clinical application.
METHODS: The key words were “drug eluting, cardiovascular stent, biocompatibility, elderly, intervention”. We retrieved Wanfang Database and China National Knowledge Infrastructure from January 1995 to October 2010. Articles concerning drug-eluting stent in elderly cardiovascular disease were included. Articles of repetitive study or Meta analysis were excluded. Using 25 articles, we analyzed the compatibility of drug-eluting stent in elderly cardiovascular diseases.
RESULTS AND CONCLUSION: Elderly patients with coronary atherosclerotic heart disease became more and more. The therapeutic effect and application of stent implantation have been verified by evidence-based medicine. However, because of the age and physical and mental conditions of elderly patients, stent implantation-induced thrombus, aneurysm and stent displacement, the safety and biocompatibility of stent implantation in elderly patients should be high. The appearance of drug-eluting stent perfectly combined cardiovascular intervention and local slow release, greatly reduced the rate of vascular restenosis of traditional stent, elevated biocompatibility after stent implantation, and brought good perspective for elderly cardiovascular disease.