Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (29): 5409-5412.doi: 10.3969/j.issn.1673-8225.2011.29.022

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Application of the HEAL-ALL tissue patch on the prevention of dry socket syndrome after tooth extraction

Huang Dai-ying, Nie Er-min, Guo Jun-bing, Ji Li   

  1. Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou  510080, Guangdong Province, China
  • Received:2011-01-11 Revised:2011-02-17 Online:2011-07-16 Published:2011-07-16
  • Contact: Ji Li, Master, Attending physician, Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
  • About author:Huang Dai-ying★, Master, Attending physician, Department of Stomatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China niean_1999@163.com
  • Supported by:

    Science and Technology Planning Project of Guangdong Province, China, No. 2008B060600018*

Abstract:

BACKGROUND: Oral tissue patch is a kind of extracellular matrix that allograft tissue treated by decellularized treatment, which has a good histocompatibility, sufficient resource and simple operation, and has been widely used in oral and maxillary surgery.
OBJECTIVE: To evaluate the effect of HEAL-ALL tissue patch on the prevention of dry socket syndrome after tooth extraction
METHODS: A total of 80 patients who had been extracted mandibular third molar were selected in the First Affiliated Hospital of Sun Yat-sen University, which were randomly divided into 2 groups. In the experimental group, oral tissue patches were put into the sockets after mandibular third molars were extracted, while in the control group, we let the wounds to be healed naturally without any materials. The incidence of dry socket syndrome was observed after 1 week.
RESULTS AND CONCLUSION: No patient had dry socket after operation in the experimental group, but in the control group, 6 patients suffered from dry socket. There was a significant difference in the incidence between the two groups (P < 0.05). In order to prevent the incidence of dry socket, especially in very difficult cases which are more traumatic and time-consuming, it is a good choice to put the oral tissue patch into socket after operation to prevent dry socket.

CLC Number: